About 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide
3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide (PubChem CID 10074987) has the molecular formula C20H15F3N6O3S2
and a molecular weight of 508.51 g/mol. Its IUPAC name is 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide.
Molecular Properties
| Compound Name | 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide |
| PubChem CID | 10074987 |
| Molecular Formula | C20H15F3N6O3S2 |
| Molecular Weight | 508.51 g/mol |
| Exact Mass | 508.06 |
| IUPAC Name | 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide |
| SMILES | O=C(NS(=O)(=O)c1cccs1)c1cccc(-n2cnc3c(NC4CC4)nc(C(F)(F)F)nc32)c1 |
| InChI | InChI=1S/C20H15F3N6O3S2/c21-20(22,23)19-26-16(25-12-6-7-12)15-17(27-19)29(10-24-15)13-4-1-3-11(9-13)18(30)28-34(31,32)14-5-2-8-33-14/h1-5,8-10,12H,6-7H2,(H,28,30)(H,25,26,27) |
| InChIKey | RRXWGSKNIDDRMP-UHFFFAOYSA-N |
| XLogP | 3.59 |
| TPSA | 118.87 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 508.51 |
| LogP ≤ 5 | 3.59 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 9 |
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Frequently Asked Questions
What is the IUPAC name of 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide?
The IUPAC name of 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide (CID 10074987) is 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide.
What is the SMILES notation for 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide?
The canonical SMILES for 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide is O=C(NS(=O)(=O)c1cccs1)c1cccc(-n2cnc3c(NC4CC4)nc(C(F)(F)F)nc32)c1.
What is the InChIKey of 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide?
The InChIKey is RRXWGSKNIDDRMP-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H15F3N6O3S2/c21-20(22,23)19-26-16(25-12-6-7-12)15-17(27-19)29(10-24-15)13-4-1-3-11(9-13)18(30)28-34(31,32)14-5-2-8-33-14/h1-5,8-10,12H,6-7H2,(H,28,30)(H,25,26,27).
What are the key properties of 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide?
3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide has a molecular weight of 508.51 g/mol, XLogP of 3.59, 6 rotatable bonds, 2 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-(cyclopropylamino)-2-(trifluoromethyl)purin-9-yl]-N-thiophen-2-ylsulfonylbenzamide is sourced from PubChem (CID 10074987), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).