4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine

C20H15ClFN5 — CID 10110282

IUPAC4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine
SMILESFc1ccc(-c2nn3c(Cl)cccc3c2-c2ccnc(NC3CC3)n2)cc1
InChIInChI=1S/C20H15ClFN5/c21-17-3-1-2-16-18(15-10-11-23-20(25-15)24-14-8-9-14)19(26-27(16)17)12-4-6-13(22)7-5-12/h1-7,10-11,14H,8-9H2,(H,23,24,25)
InChIKeyUPZNIWHYDALZKC-UHFFFAOYSA-N
MW379.83 g/mol
LogP4.83
Rot. Bonds4

About 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine

4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine (PubChem CID 10110282) has the molecular formula C20H15ClFN5 and a molecular weight of 379.83 g/mol. Its IUPAC name is 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine.

Molecular Properties

Compound Name4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine
PubChem CID10110282
Molecular FormulaC20H15ClFN5
Molecular Weight379.83 g/mol
Exact Mass379.10
IUPAC Name4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine
SMILESFc1ccc(-c2nn3c(Cl)cccc3c2-c2ccnc(NC3CC3)n2)cc1
InChIInChI=1S/C20H15ClFN5/c21-17-3-1-2-16-18(15-10-11-23-20(25-15)24-14-8-9-14)19(26-27(16)17)12-4-6-13(22)7-5-12/h1-7,10-11,14H,8-9H2,(H,23,24,25)
InChIKeyUPZNIWHYDALZKC-UHFFFAOYSA-N
XLogP4.83
TPSA55.11 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500379.83
LogP ≤ 54.83
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

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Related Compounds

4-[7-chloro-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopentylpyrimidin-2-amine
CID 57444748
3-[2-(cyclopentylamino)pyrimidin-4-yl]-2-(4-fluorophenyl)-7-methylpyrazolo[1,5-a]pyridine-6-carboxylic acid
CID 10274363
2-(3-chlorophenyl)-N-cyclopentyl-3-[2-(cyclopentylamino)pyrimidin-4-yl]pyrazolo[1,5-a]pyridin-7-amine
CID 10205592
7-(cyclopentylamino)-3-[2-(cyclopentylamino)pyrimidin-4-yl]-2-(4-fluorophenyl)-N,N-dimethylpyrazolo[1,5-a]pyridine-6-carboxamide
CID 10279925
3-[2-(cyclopentylamino)pyrimidin-4-yl]-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-6-amine;dihydrochloride
CID 131726109
3-[2-(cyclopropylamino)pyrimidin-4-yl]-2-(4-fluorophenyl)-N,N-dimethylpyrazolo[1,5-a]pyridine-6-carboxamide
CID 10112596
5-chloro-3-[2-(cyclopentylamino)pyrimidin-4-yl]-N-cyclopropyl-2-(3-methylphenyl)pyrazolo[1,5-a]pyridin-7-amine
CID 10115398
1-[3-[2-(cyclopentylamino)-6-phenylpyrimidin-4-yl]-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]ethane-1,2-diamine
CID 69449301
N-cyclopentyl-3-[2-(cyclopentylamino)pyrimidin-4-yl]-2-(3-methoxyphenyl)pyrazolo[1,5-a]pyridin-7-amine
CID 10298784
N-cyclopentyl-4-[2-(4-fluorophenyl)-6-(triethoxymethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-amine
CID 22174844
2-[4-[[3-[2-(cyclopentylamino)pyrimidin-4-yl]-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-7-yl]amino]butyl]guanidine
CID 10229481
N-cyclopentyl-2-[2-(cyclopentylamino)-4-pyridinyl]-3-[2-(propan-2-ylamino)pyrimidin-4-yl]pyrazolo[1,5-a]pyridin-7-amine
CID 10289087

Frequently Asked Questions

What is the IUPAC name of 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine?
The IUPAC name of 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine (CID 10110282) is 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine.
What is the SMILES notation for 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine?
The canonical SMILES for 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine is Fc1ccc(-c2nn3c(Cl)cccc3c2-c2ccnc(NC3CC3)n2)cc1.
What is the InChIKey of 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine?
The InChIKey is UPZNIWHYDALZKC-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H15ClFN5/c21-17-3-1-2-16-18(15-10-11-23-20(25-15)24-14-8-9-14)19(26-27(16)17)12-4-6-13(22)7-5-12/h1-7,10-11,14H,8-9H2,(H,23,24,25).
What are the key properties of 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine?
4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine has a molecular weight of 379.83 g/mol, XLogP of 4.83, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-cyclopropylpyrimidin-2-amine is sourced from PubChem (CID 10110282), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).