N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine

C18H14BrClN6 — CID 10320456

IUPACN-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine
SMILESNc1ncc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1
InChIInChI=1S/C18H14BrClN6/c19-16-9-23-17-15(22-6-11-7-24-18(21)25-8-11)5-12(10-26(16)17)13-3-1-2-4-14(13)20/h1-5,7-10,22H,6H2,(H2,21,24,25)
InChIKeyKNWLQDLQPQQOSM-UHFFFAOYSA-N
MW429.71 g/mol
LogP4.40
Rot. Bonds4

About N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine

N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine (PubChem CID 10320456) has the molecular formula C18H14BrClN6 and a molecular weight of 429.71 g/mol. Its IUPAC name is N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine.

Molecular Properties

Compound NameN-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine
PubChem CID10320456
Molecular FormulaC18H14BrClN6
Molecular Weight429.71 g/mol
Exact Mass428.02
IUPAC NameN-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine
SMILESNc1ncc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1
InChIInChI=1S/C18H14BrClN6/c19-16-9-23-17-15(22-6-11-7-24-18(21)25-8-11)5-12(10-26(16)17)13-3-1-2-4-14(13)20/h1-5,7-10,22H,6H2,(H2,21,24,25)
InChIKeyKNWLQDLQPQQOSM-UHFFFAOYSA-N
XLogP4.40
TPSA81.13 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500429.71
LogP ≤ 54.40
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-bromo-6-phenyl-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine
CID 10091097
3-bromo-6-(2-chlorocyclohexa-1,5-dien-1-yl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine
CID 142877179
5-(2-chlorophenyl)pyrimidin-2-amine
CID 66520129
8-N-benzyl-3-bromo-6-(2,4-dimethylphenyl)imidazo[1,2-a]pyridine-5,8-diamine;3-bromo-6-(2-chlorophenyl)-8-N-phenylimidazo[1,2-a]pyridine-5,8-diamine
CID 143426739
N-benzyl-3-bromo-6-phenylimidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-N-(furan-2-ylmethyl)-6-phenylimidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(thiophen-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate;3-chloro-6-phenyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine
CID 159344768
3-bromo-6-(2-chlorophenyl)-N-[3-(4,5-dihydroimidazol-1-yl)propyl]imidazo[1,2-a]pyrazin-8-amine
CID 143464664
2-[(2-chloroanilino)methyl]pyridin-4-amine
CID 105493854
3-bromo-6-phenyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine
CID 10452345
3-bromo-6-(2-chlorophenyl)-N-[3-(2-methylpiperidin-1-yl)propyl]imidazo[1,2-a]pyrazin-8-amine
CID 20814338
N-[(4-aminophenyl)methyl]-3-bromo-5-(2-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine;ethane
CID 142871130
1-[2-(2-chlorophenyl)pyrimidin-5-yl]-N-methylmethanamine
CID 62756584
2-bromo-3-chloro-N-[(6-methyl-3-pyridinyl)methyl]aniline
CID 103478067

Frequently Asked Questions

What is the IUPAC name of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine?
The IUPAC name of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine (CID 10320456) is N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine.
What is the SMILES notation for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine?
The canonical SMILES for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine is Nc1ncc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1.
What is the InChIKey of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine?
The InChIKey is KNWLQDLQPQQOSM-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H14BrClN6/c19-16-9-23-17-15(22-6-11-7-24-18(21)25-8-11)5-12(10-26(16)17)13-3-1-2-4-14(13)20/h1-5,7-10,22H,6H2,(H2,21,24,25).
What are the key properties of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine?
N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine has a molecular weight of 429.71 g/mol, XLogP of 4.40, 4 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine is sourced from PubChem (CID 10320456), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).