About (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid
(Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid (PubChem CID 10408531) has the molecular formula C21H16ClNO3S
and a molecular weight of 397.88 g/mol. Its IUPAC name is (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid.
Molecular Properties
| Compound Name | (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid |
| PubChem CID | 10408531 |
| Molecular Formula | C21H16ClNO3S |
| Molecular Weight | 397.88 g/mol |
| Exact Mass | 397.05 |
| IUPAC Name | (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid |
| SMILES | Cc1ccc(C(=O)N/C(=C\c2ccc(-c3ccccc3Cl)s2)C(=O)O)cc1 |
| InChI | InChI=1S/C21H16ClNO3S/c1-13-6-8-14(9-7-13)20(24)23-18(21(25)26)12-15-10-11-19(27-15)16-4-2-3-5-17(16)22/h2-12H,1H3,(H,23,24)(H,25,26)/b18-12- |
| InChIKey | UCUXDHFAUWUVFF-PDGQHHTCSA-N |
| XLogP | 5.23 |
| TPSA | 66.40 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 397.88 |
| LogP ≤ 5 | 5.23 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 3 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid?
The IUPAC name of (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid (CID 10408531) is (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid.
What is the SMILES notation for (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid?
The canonical SMILES for (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid is Cc1ccc(C(=O)N/C(=C\c2ccc(-c3ccccc3Cl)s2)C(=O)O)cc1.
What is the InChIKey of (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid?
The InChIKey is UCUXDHFAUWUVFF-PDGQHHTCSA-N. The full InChI is InChI=1S/C21H16ClNO3S/c1-13-6-8-14(9-7-13)20(24)23-18(21(25)26)12-15-10-11-19(27-15)16-4-2-3-5-17(16)22/h2-12H,1H3,(H,23,24)(H,25,26)/b18-12-.
What are the key properties of (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid?
(Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid has a molecular weight of 397.88 g/mol, XLogP of 5.23, 5 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (Z)-3-[5-(2-chlorophenyl)thiophen-2-yl]-2-[(4-methylbenzoyl)amino]prop-2-enoic acid is sourced from PubChem (CID 10408531), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).