6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine

C8H5F3N4S — CID 106784332

IUPAC6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine
SMILESNc1cncc(-c2cnc(C(F)(F)F)s2)n1
InChIInChI=1S/C8H5F3N4S/c9-8(10,11)7-14-2-5(16-7)4-1-13-3-6(12)15-4/h1-3H,(H2,12,15)
InChIKeyRMGHUMFJCLLVOQ-UHFFFAOYSA-N
MW246.22 g/mol
LogP2.20
Rot. Bonds1

About 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine

6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine (PubChem CID 106784332) has the molecular formula C8H5F3N4S and a molecular weight of 246.22 g/mol. Its IUPAC name is 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine.

Molecular Properties

Compound Name6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine
PubChem CID106784332
Molecular FormulaC8H5F3N4S
Molecular Weight246.22 g/mol
Exact Mass246.02
IUPAC Name6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine
SMILESNc1cncc(-c2cnc(C(F)(F)F)s2)n1
InChIInChI=1S/C8H5F3N4S/c9-8(10,11)7-14-2-5(16-7)4-1-13-3-6(12)15-4/h1-3H,(H2,12,15)
InChIKeyRMGHUMFJCLLVOQ-UHFFFAOYSA-N
XLogP2.20
TPSA64.69 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds1
Heavy Atoms16
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500246.22
LogP ≤ 52.20
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Frequently Asked Questions

What is the IUPAC name of 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine?
The IUPAC name of 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine (CID 106784332) is 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine.
What is the SMILES notation for 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine?
The canonical SMILES for 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine is Nc1cncc(-c2cnc(C(F)(F)F)s2)n1.
What is the InChIKey of 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine?
The InChIKey is RMGHUMFJCLLVOQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H5F3N4S/c9-8(10,11)7-14-2-5(16-7)4-1-13-3-6(12)15-4/h1-3H,(H2,12,15).
What are the key properties of 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine?
6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine has a molecular weight of 246.22 g/mol, XLogP of 2.20, 1 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[2-(trifluoromethyl)-1,3-thiazol-5-yl]pyrazin-2-amine is sourced from PubChem (CID 106784332), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).