N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide

C21H14F2N4O — CID 109200781

IUPACN-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide
SMILESO=C(Nc1c(F)cccc1F)c1ccc(Nc2cccc3cccnc23)cn1
InChIInChI=1S/C21H14F2N4O/c22-15-6-2-7-16(23)20(15)27-21(28)18-10-9-14(12-25-18)26-17-8-1-4-13-5-3-11-24-19(13)17/h1-12,26H,(H,27,28)
InChIKeyLCWZJKIAFZSQRO-UHFFFAOYSA-N
MW376.37 g/mol
LogP4.90
Rot. Bonds4

About N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide

N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide (PubChem CID 109200781) has the molecular formula C21H14F2N4O and a molecular weight of 376.37 g/mol. Its IUPAC name is N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide.

Molecular Properties

Compound NameN-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide
PubChem CID109200781
Molecular FormulaC21H14F2N4O
Molecular Weight376.37 g/mol
Exact Mass376.11
IUPAC NameN-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide
SMILESO=C(Nc1c(F)cccc1F)c1ccc(Nc2cccc3cccnc23)cn1
InChIInChI=1S/C21H14F2N4O/c22-15-6-2-7-16(23)20(15)27-21(28)18-10-9-14(12-25-18)26-17-8-1-4-13-5-3-11-24-19(13)17/h1-12,26H,(H,27,28)
InChIKeyLCWZJKIAFZSQRO-UHFFFAOYSA-N
XLogP4.90
TPSA66.91 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500376.37
LogP ≤ 54.90
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(2,6-dimethylphenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide
CID 109198241
N-[4-(dimethylamino)phenyl]-5-(quinolin-8-ylamino)pyridine-2-carboxamide
CID 109200554
N-butyl-5-(quinolin-8-ylamino)pyridine-2-carboxamide
CID 109180787
N-(2,6-difluorophenyl)-5-(2,3,4-trifluoroanilino)pyridine-2-carboxamide
CID 109200969
5-(2-methoxyanilino)-N-quinolin-8-ylpyridine-2-carboxamide
CID 109199751
5-[2-(2-fluorophenyl)ethylamino]-N-quinolin-8-ylpyridine-2-carboxamide
CID 109192303
N-(5-methyl-1,2-oxazol-3-yl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide
CID 109200783
5-(methylamino)-N-quinolin-8-ylpyridine-2-carboxamide
CID 104639694
N-(2,6-difluorophenyl)-5-(2-ethoxyanilino)pyridine-2-carboxamide
CID 109200015
5-(butylamino)-N-quinolin-8-ylpyridine-2-carboxamide
CID 109180980
N-(2,6-difluorophenyl)-5-[4-(trifluoromethyl)anilino]pyridine-2-carboxamide
CID 109200327
5-(cyclopropylamino)-N-quinolin-8-ylpyridine-2-carboxamide
CID 109180200

Frequently Asked Questions

What is the IUPAC name of N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide?
The IUPAC name of N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide (CID 109200781) is N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide.
What is the SMILES notation for N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide?
The canonical SMILES for N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide is O=C(Nc1c(F)cccc1F)c1ccc(Nc2cccc3cccnc23)cn1.
What is the InChIKey of N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide?
The InChIKey is LCWZJKIAFZSQRO-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H14F2N4O/c22-15-6-2-7-16(23)20(15)27-21(28)18-10-9-14(12-25-18)26-17-8-1-4-13-5-3-11-24-19(13)17/h1-12,26H,(H,27,28).
What are the key properties of N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide?
N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide has a molecular weight of 376.37 g/mol, XLogP of 4.90, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2,6-difluorophenyl)-5-(quinolin-8-ylamino)pyridine-2-carboxamide is sourced from PubChem (CID 109200781), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).