N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide

C18H20F2N4O — CID 109288660

IUPACN-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide
SMILESCCC1CCCCN1c1cnc(C(=O)Nc2ccc(F)cc2F)cn1
InChIInChI=1S/C18H20F2N4O/c1-2-13-5-3-4-8-24(13)17-11-21-16(10-22-17)18(25)23-15-7-6-12(19)9-14(15)20/h6-7,9-11,13H,2-5,8H2,1H3,(H,23,25)
InChIKeyVZBFHWGPNMRRDE-UHFFFAOYSA-N
MW346.38 g/mol
LogP3.78
Rot. Bonds4

About N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide

N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide (PubChem CID 109288660) has the molecular formula C18H20F2N4O and a molecular weight of 346.38 g/mol. Its IUPAC name is N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide
PubChem CID109288660
Molecular FormulaC18H20F2N4O
Molecular Weight346.38 g/mol
Exact Mass346.16
IUPAC NameN-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide
SMILESCCC1CCCCN1c1cnc(C(=O)Nc2ccc(F)cc2F)cn1
InChIInChI=1S/C18H20F2N4O/c1-2-13-5-3-4-8-24(13)17-11-21-16(10-22-17)18(25)23-15-7-6-12(19)9-14(15)20/h6-7,9-11,13H,2-5,8H2,1H3,(H,23,25)
InChIKeyVZBFHWGPNMRRDE-UHFFFAOYSA-N
XLogP3.78
TPSA58.12 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500346.38
LogP ≤ 53.78
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

5-(2-ethylpiperidin-1-yl)-N-(2,3,4-trifluorophenyl)pyrazine-2-carboxamide
CID 109288675
5-(2-ethylpiperidin-1-yl)-N-(3-fluorophenyl)pyrazine-2-carboxamide
CID 109288653
5-(2-ethylpiperidin-1-yl)-N-(2-methoxyphenyl)pyrazine-2-carboxamide
CID 109288627
N-(2,6-dimethylphenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide
CID 109288601
5-(2-ethylpiperidin-1-yl)-N-[(2-fluorophenyl)methyl]pyrazine-2-carboxamide
CID 109281326
5-(2-ethylpiperidin-1-yl)-N-quinolin-8-ylpyrazine-2-carboxamide
CID 109288658
N-cyclohexyl-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide
CID 109274707
N-(2,4-difluorophenyl)-4-(2-ethylpiperidine-1-carbonyl)pyridine-2-carboxamide
CID 109090195
methyl 5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxylate
CID 104696638
5-(2-ethylpiperidin-1-yl)-N-(3-methylbutyl)pyrazine-2-carboxamide
CID 109287769
5-(2-ethylpiperidin-1-yl)-N-(1-phenylethyl)pyrazine-2-carboxamide
CID 109280798
6-(2-ethylpiperidin-1-yl)-N-(3-fluorophenyl)pyridazine-3-carboxamide
CID 109125838

Frequently Asked Questions

What is the IUPAC name of N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide?
The IUPAC name of N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide (CID 109288660) is N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide.
What is the SMILES notation for N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide?
The canonical SMILES for N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide is CCC1CCCCN1c1cnc(C(=O)Nc2ccc(F)cc2F)cn1.
What is the InChIKey of N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide?
The InChIKey is VZBFHWGPNMRRDE-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20F2N4O/c1-2-13-5-3-4-8-24(13)17-11-21-16(10-22-17)18(25)23-15-7-6-12(19)9-14(15)20/h6-7,9-11,13H,2-5,8H2,1H3,(H,23,25).
What are the key properties of N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide?
N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide has a molecular weight of 346.38 g/mol, XLogP of 3.78, 4 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2,4-difluorophenyl)-5-(2-ethylpiperidin-1-yl)pyrazine-2-carboxamide is sourced from PubChem (CID 109288660), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).