About 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone
2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone (PubChem CID 110202643) has the molecular formula C18H18ClFN2O2
and a molecular weight of 348.81 g/mol. Its IUPAC name is 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone.
Molecular Properties
| Compound Name | 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone |
| PubChem CID | 110202643 |
| Molecular Formula | C18H18ClFN2O2 |
| Molecular Weight | 348.81 g/mol |
| Exact Mass | 348.10 |
| IUPAC Name | 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone |
| SMILES | O=C(Cc1c(F)cccc1Cl)N1C[C@@H](CO)[C@H](c2ccncc2)C1 |
| InChI | InChI=1S/C18H18ClFN2O2/c19-16-2-1-3-17(20)14(16)8-18(24)22-9-13(11-23)15(10-22)12-4-6-21-7-5-12/h1-7,13,15,23H,8-11H2/t13-,15-/m0/s1 |
| InChIKey | BNJHHZCXRKXPQN-ZFWWWQNUSA-N |
| XLogP | 2.65 |
| TPSA | 53.43 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 24 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 348.81 |
| LogP ≤ 5 | 2.65 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 3 |
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Frequently Asked Questions
What is the IUPAC name of 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone?
The IUPAC name of 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone (CID 110202643) is 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone.
What is the SMILES notation for 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone?
The canonical SMILES for 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone is O=C(Cc1c(F)cccc1Cl)N1C[C@@H](CO)[C@H](c2ccncc2)C1.
What is the InChIKey of 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone?
The InChIKey is BNJHHZCXRKXPQN-ZFWWWQNUSA-N. The full InChI is InChI=1S/C18H18ClFN2O2/c19-16-2-1-3-17(20)14(16)8-18(24)22-9-13(11-23)15(10-22)12-4-6-21-7-5-12/h1-7,13,15,23H,8-11H2/t13-,15-/m0/s1.
What are the key properties of 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone?
2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone has a molecular weight of 348.81 g/mol, XLogP of 2.65, 4 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-chloro-6-fluorophenyl)-1-[(3S,4R)-3-(hydroxymethyl)-4-pyridin-4-ylpyrrolidin-1-yl]ethanone is sourced from PubChem (CID 110202643), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).