5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine

C18H20N6S — CID 110262807

IUPAC5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine
SMILESCc1cc(Nc2ncc(C)s2)cc(C2CCCN2c2ncccn2)n1
InChIInChI=1S/C18H20N6S/c1-12-9-14(23-18-21-11-13(2)25-18)10-15(22-12)16-5-3-8-24(16)17-19-6-4-7-20-17/h4,6-7,9-11,16H,3,5,8H2,1-2H3,(H,21,22,23)
InChIKeyXPTXJWLEWFUCFT-UHFFFAOYSA-N
MW352.47 g/mol
LogP4.03
Rot. Bonds4

About 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine

5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine (PubChem CID 110262807) has the molecular formula C18H20N6S and a molecular weight of 352.47 g/mol. Its IUPAC name is 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine.

Molecular Properties

Compound Name5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine
PubChem CID110262807
Molecular FormulaC18H20N6S
Molecular Weight352.47 g/mol
Exact Mass352.15
IUPAC Name5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine
SMILESCc1cc(Nc2ncc(C)s2)cc(C2CCCN2c2ncccn2)n1
InChIInChI=1S/C18H20N6S/c1-12-9-14(23-18-21-11-13(2)25-18)10-15(22-12)16-5-3-8-24(16)17-19-6-4-7-20-17/h4,6-7,9-11,16H,3,5,8H2,1-2H3,(H,21,22,23)
InChIKeyXPTXJWLEWFUCFT-UHFFFAOYSA-N
XLogP4.03
TPSA66.83 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500352.47
LogP ≤ 54.03
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

Analyze 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine with MolForge

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Related Compounds

N-[2-[(2R)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]pyrrolidin-2-yl]-6-methyl-4-pyridinyl]-5-methyl-1,3-thiazol-2-amine
CID 95832813
N-[2-[(2S)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]pyrrolidin-2-yl]-6-methyl-4-pyridinyl]-5-methyl-1,3-thiazol-2-amine
CID 95832812
2-[(3R)-3-[6-methyl-4-(pyridin-2-ylamino)-2-pyridinyl]piperidin-1-yl]-N-(5-methyl-1,3-thiazol-2-yl)acetamide
CID 95834814
(2-methyl-1,3-benzothiazol-6-yl)-[(2R)-2-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]methanone
CID 95832737
2,3-dihydro-1,4-benzodioxin-6-yl-[(2R)-2-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]methanone
CID 95832617
(3R)-N,N-dimethyl-3-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]piperidine-1-sulfonamide
CID 124949686
2-(2,4-difluorophenoxy)-1-[(2R)-2-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]ethanone
CID 95832743
2-methyl-N-pyrimidin-2-yl-6-[(2R)-1-pyrimidin-2-ylpyrrolidin-2-yl]pyrimidin-4-amine
CID 95820566
N,2-dimethyl-6-[(2S)-1-pyrimidin-2-ylpyrrolidin-2-yl]pyrimidin-4-amine
CID 124986346
1-[(2S)-2-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]-3-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)propan-1-one
CID 95832856
1-[2-[6-methyl-4-[(5-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]-3-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)propan-1-one
CID 110262904
3-[5-[1-[4-methyl-6-[(5-methyl-1,3-thiazol-2-yl)amino]pyrimidin-2-yl]pyrrolidin-2-yl]-1,2-oxazol-3-yl]pyridine-2-carbonitrile
CID 73231021

Frequently Asked Questions

What is the IUPAC name of 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine?
The IUPAC name of 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine (CID 110262807) is 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine.
What is the SMILES notation for 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine?
The canonical SMILES for 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine is Cc1cc(Nc2ncc(C)s2)cc(C2CCCN2c2ncccn2)n1.
What is the InChIKey of 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine?
The InChIKey is XPTXJWLEWFUCFT-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20N6S/c1-12-9-14(23-18-21-11-13(2)25-18)10-15(22-12)16-5-3-8-24(16)17-19-6-4-7-20-17/h4,6-7,9-11,16H,3,5,8H2,1-2H3,(H,21,22,23).
What are the key properties of 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine?
5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine has a molecular weight of 352.47 g/mol, XLogP of 4.03, 4 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-methyl-N-[2-methyl-6-(1-pyrimidin-2-ylpyrrolidin-2-yl)-4-pyridinyl]-1,3-thiazol-2-amine is sourced from PubChem (CID 110262807), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).