1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol

C11H18F3NO2 — CID 111432870

IUPAC1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol
SMILESOC1CCN(C(C2CCCO2)C(F)(F)F)CC1
InChIInChI=1S/C11H18F3NO2/c12-11(13,14)10(9-2-1-7-17-9)15-5-3-8(16)4-6-15/h8-10,16H,1-7H2
InChIKeyRUOKSDXXMJWSPS-UHFFFAOYSA-N
MW253.26 g/mol
LogP1.55
Rot. Bonds2

About 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol

1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol (PubChem CID 111432870) has the molecular formula C11H18F3NO2 and a molecular weight of 253.26 g/mol. Its IUPAC name is 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol.

Molecular Properties

Compound Name1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol
PubChem CID111432870
Molecular FormulaC11H18F3NO2
Molecular Weight253.26 g/mol
Exact Mass253.13
IUPAC Name1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol
SMILESOC1CCN(C(C2CCCO2)C(F)(F)F)CC1
InChIInChI=1S/C11H18F3NO2/c12-11(13,14)10(9-2-1-7-17-9)15-5-3-8(16)4-6-15/h8-10,16H,1-7H2
InChIKeyRUOKSDXXMJWSPS-UHFFFAOYSA-N
XLogP1.55
TPSA32.70 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms17
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500253.26
LogP ≤ 51.55
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

Analyze 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1,1,1-Trifluoro-3-[oxan-2-ylmethyl(propan-2-yl)amino]propan-2-ol
CID 75507584
[(6S,8aS)-3,3-difluoro-1,4,6,7,8,8a-hexahydropyrrolo[2,1-c][1,4]oxazin-6-yl]methanol
CID 165405634
[5-(3-Fluoropropyl)-2-oxa-5-azabicyclo[2.2.1]heptan-6-yl]methanol
CID 169228003
3,3,3-Trifluoro-2-(3-oxa-8-azabicyclo[3.2.1]octan-8-ylmethyl)propan-1-ol
CID 170082286
(2S)-2-fluoro-3-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)propan-1-ol
CID 170083577
(2R)-3,3,3-trifluoro-2-(3-oxa-8-azabicyclo[3.2.1]octan-8-ylmethyl)propan-1-ol
CID 170083823
(2S)-3,3,3-trifluoro-2-(3-oxa-8-azabicyclo[3.2.1]octan-8-ylmethyl)propan-1-ol
CID 170107834
(3,3-Difluoro-1,4,6,7,8,8a-hexahydropyrrolo[2,1-c][1,4]oxazin-6-yl)methanol
CID 178932540
4-[2,2,2-Trifluoro-1-(oxolan-2-yl)ethyl]morpholine
CID 54594391
[1-[2-(2,2,2-Trifluoroethoxy)ethyl]piperidin-2-yl]methanol
CID 61327950
[1-[3-(2,2,2-Trifluoroethoxy)propyl]piperidin-2-yl]methanol
CID 61355392
2-[1-[2-(2,2,2-Trifluoroethoxy)ethyl]piperidin-2-yl]ethanol
CID 62019928

Frequently Asked Questions

What is the IUPAC name of 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol?
The IUPAC name of 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol (CID 111432870) is 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol.
What is the SMILES notation for 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol?
The canonical SMILES for 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol is OC1CCN(C(C2CCCO2)C(F)(F)F)CC1.
What is the InChIKey of 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol?
The InChIKey is RUOKSDXXMJWSPS-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H18F3NO2/c12-11(13,14)10(9-2-1-7-17-9)15-5-3-8(16)4-6-15/h8-10,16H,1-7H2.
What are the key properties of 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol?
1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol has a molecular weight of 253.26 g/mol, XLogP of 1.55, 2 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[2,2,2-trifluoro-1-(oxolan-2-yl)ethyl]piperidin-4-ol is sourced from PubChem (CID 111432870), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).