About 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid
2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid (PubChem CID 11153727) has the molecular formula C18H11ClF3NO4
and a molecular weight of 397.74 g/mol. Its IUPAC name is 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid.
Molecular Properties
| Compound Name | 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid |
| PubChem CID | 11153727 |
| Molecular Formula | C18H11ClF3NO4 |
| Molecular Weight | 397.74 g/mol |
| Exact Mass | 397.03 |
| IUPAC Name | 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid |
| SMILES | O=C(O)c1c(O)c(Cc2ccc(Cl)cc2)nc2c(OC(F)(F)F)cccc12 |
| InChI | InChI=1S/C18H11ClF3NO4/c19-10-6-4-9(5-7-10)8-12-16(24)14(17(25)26)11-2-1-3-13(15(11)23-12)27-18(20,21)22/h1-7,24H,8H2,(H,25,26) |
| InChIKey | FCDSQVFIXQXOQB-UHFFFAOYSA-N |
| XLogP | 4.78 |
| TPSA | 79.65 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 397.74 |
| LogP ≤ 5 | 4.78 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid?
The IUPAC name of 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid (CID 11153727) is 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid.
What is the SMILES notation for 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid?
The canonical SMILES for 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid is O=C(O)c1c(O)c(Cc2ccc(Cl)cc2)nc2c(OC(F)(F)F)cccc12.
What is the InChIKey of 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid?
The InChIKey is FCDSQVFIXQXOQB-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H11ClF3NO4/c19-10-6-4-9(5-7-10)8-12-16(24)14(17(25)26)11-2-1-3-13(15(11)23-12)27-18(20,21)22/h1-7,24H,8H2,(H,25,26).
What are the key properties of 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid?
2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid has a molecular weight of 397.74 g/mol, XLogP of 4.78, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid is sourced from PubChem (CID 11153727), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).