About 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid
4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid (PubChem CID 11226553) has the molecular formula C29H25ClN4O5
and a molecular weight of 545.00 g/mol. Its IUPAC name is 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid.
Molecular Properties
| Compound Name | 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid |
| PubChem CID | 11226553 |
| Molecular Formula | C29H25ClN4O5 |
| Molecular Weight | 545.00 g/mol |
| Exact Mass | 544.15 |
| IUPAC Name | 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid |
| SMILES | O=C(O)CCC(=O)c1cn(-c2nc(N3CCC(O)CC3)c3cc(-c4ccco4)ccc3n2)c2ccc(Cl)cc12 |
| InChI | InChI=1S/C29H25ClN4O5/c30-18-4-6-24-20(15-18)22(25(36)7-8-27(37)38)16-34(24)29-31-23-5-3-17(26-2-1-13-39-26)14-21(23)28(32-29)33-11-9-19(35)10-12-33/h1-6,13-16,19,35H,7-12H2,(H,37,38) |
| InChIKey | HMKBHXQQWBJZKY-UHFFFAOYSA-N |
| XLogP | 5.50 |
| TPSA | 121.69 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 39 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 545.00 |
| LogP ≤ 5 | 5.50 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 8 |
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Frequently Asked Questions
What is the IUPAC name of 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid?
The IUPAC name of 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid (CID 11226553) is 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid.
What is the SMILES notation for 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid?
The canonical SMILES for 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid is O=C(O)CCC(=O)c1cn(-c2nc(N3CCC(O)CC3)c3cc(-c4ccco4)ccc3n2)c2ccc(Cl)cc12.
What is the InChIKey of 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid?
The InChIKey is HMKBHXQQWBJZKY-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H25ClN4O5/c30-18-4-6-24-20(15-18)22(25(36)7-8-27(37)38)16-34(24)29-31-23-5-3-17(26-2-1-13-39-26)14-21(23)28(32-29)33-11-9-19(35)10-12-33/h1-6,13-16,19,35H,7-12H2,(H,37,38).
What are the key properties of 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid?
4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid has a molecular weight of 545.00 g/mol, XLogP of 5.50, 7 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[5-chloro-1-[6-(furan-2-yl)-4-(4-hydroxypiperidin-1-yl)quinazolin-2-yl]indol-3-yl]-4-oxobutanoic acid is sourced from PubChem (CID 11226553), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).