6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine

C20H16F3N5O — CID 118094686

IUPAC6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine
SMILESCOc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(C)cc4)n3)n2c1
InChIInChI=1S/C20H16F3N5O/c1-12-3-5-13(6-4-12)25-16-10-24-9-15(26-16)18-19(20(21,22)23)27-17-8-7-14(29-2)11-28(17)18/h3-11H,1-2H3,(H,25,26)
InChIKeySCJHPIZEDIJSFA-UHFFFAOYSA-N
MW399.38 g/mol
LogP4.87
Rot. Bonds4

About 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine

6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine (PubChem CID 118094686) has the molecular formula C20H16F3N5O and a molecular weight of 399.38 g/mol. Its IUPAC name is 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine.

Molecular Properties

Compound Name6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine
PubChem CID118094686
Molecular FormulaC20H16F3N5O
Molecular Weight399.38 g/mol
Exact Mass399.13
IUPAC Name6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine
SMILESCOc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(C)cc4)n3)n2c1
InChIInChI=1S/C20H16F3N5O/c1-12-3-5-13(6-4-12)25-16-10-24-9-15(26-16)18-19(20(21,22)23)27-17-8-7-14(29-2)11-28(17)18/h3-11H,1-2H3,(H,25,26)
InChIKeySCJHPIZEDIJSFA-UHFFFAOYSA-N
XLogP4.87
TPSA64.34 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms29
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500399.38
LogP ≤ 54.87
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

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Related Compounds

N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine
CID 118094925
6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine
CID 118094659
N-(4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine
CID 91799361
4-[[6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-2-pyridinyl]amino]phenol
CID 118094614
2-methoxy-N-[6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-yl]pyrimidin-5-amine
CID 118101407
2-[6-bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methoxyphenyl)pyrimidin-4-amine;2-[6-bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrimidin-4-amine
CID 162144012
2-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile
CID 118095092
6-[2-(methylideneamino)-3-[(Z)-prop-1-enyl]-5-(trifluoromethyl)imidazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
CID 144848728
N-[4-(difluoromethoxy)-3-fluorophenyl]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine
CID 118094982
6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-(4-methoxyphenyl)pyridin-2-amine
CID 118094774
2-(trifluoromethyl)-3-[6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridin-6-ol
CID 118101535
2-N-(4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-2,5-diamine
CID 118101444

Frequently Asked Questions

What is the IUPAC name of 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine?
The IUPAC name of 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine (CID 118094686) is 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine.
What is the SMILES notation for 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine?
The canonical SMILES for 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine is COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(C)cc4)n3)n2c1.
What is the InChIKey of 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine?
The InChIKey is SCJHPIZEDIJSFA-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H16F3N5O/c1-12-3-5-13(6-4-12)25-16-10-24-9-15(26-16)18-19(20(21,22)23)27-17-8-7-14(29-2)11-28(17)18/h3-11H,1-2H3,(H,25,26).
What are the key properties of 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine?
6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine has a molecular weight of 399.38 g/mol, XLogP of 4.87, 4 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-(4-methylphenyl)pyrazin-2-amine is sourced from PubChem (CID 118094686), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).