C37H48N6O8 — CID 118122265
ethyl (2Z)-2-[4-[2-[(5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-3-morpholin-4-ylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]-1-(pyridin-2-ylamino)ethyl]-5-oxofuran-2-ylidene]-2-(2-aminopyrimidin-5-yl)acetate (PubChem CID 118122265) has the molecular formula C37H48N6O8 and a molecular weight of 704.83 g/mol. Its IUPAC name is ethyl (2Z)-2-[4-[2-[(5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-3-morpholin-4-ylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]-1-(pyridin-2-ylamino)ethyl]-5-oxofuran-2-ylidene]-2-(2-aminopyrimidin-5-yl)acetate.
| Compound Name | ethyl (2Z)-2-[4-[2-[(5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-3-morpholin-4-ylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]-1-(pyridin-2-ylamino)ethyl]-5-oxofuran-2-ylidene]-2-(2-aminopyrimidin-5-yl)acetate |
|---|---|
| PubChem CID | 118122265 |
| Molecular Formula | C37H48N6O8 |
| Molecular Weight | 704.83 g/mol |
| Exact Mass | 704.35 |
| IUPAC Name | ethyl (2Z)-2-[4-[2-[(5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-3-morpholin-4-ylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]-1-(pyridin-2-ylamino)ethyl]-5-oxofuran-2-ylidene]-2-(2-aminopyrimidin-5-yl)acetate |
| SMILES | CCOC(=O)/C(=C1/C=C(C(CC2C3(CO3)C(N3CCOCC3)CC3[C@]2(C)CC[C@@H](O)[C@@]3(C)CO)Nc2ccccn2)C(=O)O1)c1cnc(N)nc1 |
| InChI | InChI=1S/C37H48N6O8/c1-4-49-33(47)31(22-18-40-34(38)41-19-22)25-15-23(32(46)51-25)24(42-30-7-5-6-10-39-30)16-27-35(2)9-8-29(45)36(3,20-44)26(35)17-28(37(27)21-50-37)43-11-13-48-14-12-43/h5-7,10,15,18-19,24,26-29,44-45H,4,8-9,11-14,16-17,20-21H2,1-3H3,(H,39,42)(H2,38,40,41)/b31-25-/t24?,26?,27?,28?,29-,35+,36+,37?/m1/s1 |
| InChIKey | PALSIZDVLJOOFA-DUFWWKPOSA-N |
| XLogP | 2.35 |
| TPSA | 194.78 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 14 |
| Rotatable Bonds | 10 |
| Heavy Atoms | 51 |
| Complexity | — |
2 violations
| Rule | Value |
|---|---|
| MW ≤ 500 | 704.83 |
| LogP ≤ 5 | 2.35 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 14 |
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'Three-membered_heterocycle', 'substructure': 'N/A'} |
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