5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide

C19H17F2N5O2 — CID 118130793

IUPAC5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide
SMILESCOc1cc(C2CC2)ncc1-c1cc(C(=O)Nc2c(F)cncc2F)nn1C
InChIInChI=1S/C19H17F2N5O2/c1-26-16(11-7-23-14(10-3-4-10)6-17(11)28-2)5-15(25-26)19(27)24-18-12(20)8-22-9-13(18)21/h5-10H,3-4H2,1-2H3,(H,22,24,27)
InChIKeyQAUIRYKGFHOYRW-UHFFFAOYSA-N
MW385.37 g/mol
LogP3.29
Rot. Bonds5

About 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide

5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide (PubChem CID 118130793) has the molecular formula C19H17F2N5O2 and a molecular weight of 385.37 g/mol. Its IUPAC name is 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide.

Molecular Properties

Compound Name5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide
PubChem CID118130793
Molecular FormulaC19H17F2N5O2
Molecular Weight385.37 g/mol
Exact Mass385.14
IUPAC Name5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide
SMILESCOc1cc(C2CC2)ncc1-c1cc(C(=O)Nc2c(F)cncc2F)nn1C
InChIInChI=1S/C19H17F2N5O2/c1-26-16(11-7-23-14(10-3-4-10)6-17(11)28-2)5-15(25-26)19(27)24-18-12(20)8-22-9-13(18)21/h5-10H,3-4H2,1-2H3,(H,22,24,27)
InChIKeyQAUIRYKGFHOYRW-UHFFFAOYSA-N
XLogP3.29
TPSA81.93 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500385.37
LogP ≤ 53.29
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

Analyze 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide with MolForge

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Related Compounds

4-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide
CID 145925694
N-[1-(3-methoxyphenyl)-4,5,6,7-tetrahydroindazol-4-yl]pyridine-2-carboxamide
CID 50898239
N-(3-methoxyphenyl)-1-propyl-5-(2-pyridin-4-ylethylamino)-4,5,6,7-tetrahydroindazole-3-carboxamide
CID 146641578
N-(5-((2S,5R,6R)-5-Amino-6-fluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-6-(2,6-difluoro-4-methoxyphenyl)-5-fluoropicolinamide
CID 73437807
N-(5-((2S,5R,6S)-5-amino-6-fluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-6-(2,6-difluoro-4-methoxyphenyl)-5-fluoropicolinamide
CID 73438188
N-(5-((2S,5R,6S)-5-amino-6-fluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-5-fluoro-6-(2-fluoro-4-methoxyphenyl)picolinamide
CID 86713898
N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(triazol-1-yl)piperidin-1-yl]-3-pyridinyl]-6-(2,6-difluoro-4-propan-2-yloxyphenyl)-5-fluoropyridine-2-carboxamide
CID 91937603
N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(triazol-1-yl)piperidin-1-yl]-3-pyridinyl]-6-(2,6-difluoro-4-methoxyphenyl)-5-fluoropyridine-2-carboxamide
CID 91937644
US11034658, Example 9
CID 153296722
US11034658, Example 49
CID 153296756
N-(2-methoxy-4-pyridinyl)-2-phenylpyrazolo[1,5-a]pyridine-6-carboxamide
CID 165414996
N-{[4-(Propan-2-yloxy)phenyl]methyl}pyrazolo[1,5-A]pyridine-2-carboxamide
CID 16024936

Frequently Asked Questions

What is the IUPAC name of 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide?
The IUPAC name of 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide (CID 118130793) is 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide.
What is the SMILES notation for 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide?
The canonical SMILES for 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide is COc1cc(C2CC2)ncc1-c1cc(C(=O)Nc2c(F)cncc2F)nn1C.
What is the InChIKey of 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide?
The InChIKey is QAUIRYKGFHOYRW-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H17F2N5O2/c1-26-16(11-7-23-14(10-3-4-10)6-17(11)28-2)5-15(25-26)19(27)24-18-12(20)8-22-9-13(18)21/h5-10H,3-4H2,1-2H3,(H,22,24,27).
What are the key properties of 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide?
5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide has a molecular weight of 385.37 g/mol, XLogP of 3.29, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(6-cyclopropyl-4-methoxy-3-pyridinyl)-N-(3,5-difluoro-4-pyridinyl)-1-methylpyrazole-3-carboxamide is sourced from PubChem (CID 118130793), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).