8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

C23H23F2N5O3 — CID 118321192

IUPAC8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
SMILESCc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1ccn(C)n1
InChIInChI=1S/C23H23F2N5O3/c1-14-20(22(32)27-23(2,13-31)19-9-11-29(3)28-19)30-10-5-8-18(21(30)26-14)33-12-15-16(24)6-4-7-17(15)25/h4-11,31H,12-13H2,1-3H3,(H,27,32)
InChIKeyLGGILRLWDKGBMK-UHFFFAOYSA-N
MW455.47 g/mol
LogP2.87
Rot. Bonds7

About 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 118321192) has the molecular formula C23H23F2N5O3 and a molecular weight of 455.47 g/mol. Its IUPAC name is 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

Compound Name8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
PubChem CID118321192
Molecular FormulaC23H23F2N5O3
Molecular Weight455.47 g/mol
Exact Mass455.18
IUPAC Name8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
SMILESCc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1ccn(C)n1
InChIInChI=1S/C23H23F2N5O3/c1-14-20(22(32)27-23(2,13-31)19-9-11-29(3)28-19)30-10-5-8-18(21(30)26-14)33-12-15-16(24)6-4-7-17(15)25/h4-11,31H,12-13H2,1-3H3,(H,27,32)
InChIKeyLGGILRLWDKGBMK-UHFFFAOYSA-N
XLogP2.87
TPSA93.68 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds7
Heavy Atoms33
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500455.47
LogP ≤ 52.87
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CID 118321192) is 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.
What is the SMILES notation for 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The canonical SMILES for 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1ccn(C)n1.
What is the InChIKey of 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
The InChIKey is LGGILRLWDKGBMK-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23F2N5O3/c1-14-20(22(32)27-23(2,13-31)19-9-11-29(3)28-19)30-10-5-8-18(21(30)26-14)33-12-15-16(24)6-4-7-17(15)25/h4-11,31H,12-13H2,1-3H3,(H,27,32).
What are the key properties of 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?
8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 455.47 g/mol, XLogP of 2.87, 7 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 8-[(2,6-difluorophenyl)methoxy]-N-[1-hydroxy-2-(1-methylpyrazol-3-yl)propan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 118321192), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).