6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine

C16H16F3N3O — CID 118484366

IUPAC6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine
SMILESFC(F)(F)c1ccc(Nc2ccc([C@H]3CNCCO3)nc2)cc1
InChIInChI=1S/C16H16F3N3O/c17-16(18,19)11-1-3-12(4-2-11)22-13-5-6-14(21-9-13)15-10-20-7-8-23-15/h1-6,9,15,20,22H,7-8,10H2/t15-/m1/s1
InChIKeyCWRDKDSHVOKMNB-OAHLLOKOSA-N
MW323.32 g/mol
LogP3.50
Rot. Bonds3

About 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine

6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine (PubChem CID 118484366) has the molecular formula C16H16F3N3O and a molecular weight of 323.32 g/mol. Its IUPAC name is 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine.

Molecular Properties

Compound Name6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine
PubChem CID118484366
Molecular FormulaC16H16F3N3O
Molecular Weight323.32 g/mol
Exact Mass323.12
IUPAC Name6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine
SMILESFC(F)(F)c1ccc(Nc2ccc([C@H]3CNCCO3)nc2)cc1
InChIInChI=1S/C16H16F3N3O/c17-16(18,19)11-1-3-12(4-2-11)22-13-5-6-14(21-9-13)15-10-20-7-8-23-15/h1-6,9,15,20,22H,7-8,10H2/t15-/m1/s1
InChIKeyCWRDKDSHVOKMNB-OAHLLOKOSA-N
XLogP3.50
TPSA46.18 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500323.32
LogP ≤ 53.50
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

2-[3-[(4-Phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]pyridine
CID 58993510
(2S)-2-[4-[4-(4-fluorophenyl)triazol-1-yl]phenyl]morpholine
CID 71656893
(2R)-2-[4-[4-(4-fluorophenyl)triazol-1-yl]phenyl]morpholine
CID 71656894
N-Desmethyldoxylamine
CID 135338
N-(4-morpholin-2-ylphenyl)-5-(trifluoromethyl)pyridine-2-carboxamide
CID 53251568
N-(4-morpholin-2-ylphenyl)-2-(trifluoromethyl)pyridine-4-carboxamide
CID 66705980
N-[4-[(2S)-morpholin-2-yl]phenyl]-4-(trifluoromethyl)pyridin-2-amine
CID 68325398
N-[4-[(2R)-morpholin-2-yl]phenyl]-5-(trifluoromethyl)pyrazin-2-amine
CID 68325436
N-(4-morpholin-2-ylphenyl)-5-(trifluoromethyl)pyridin-2-amine
CID 68325509
N-[4-[(2R)-morpholin-2-yl]phenyl]-4-(trifluoromethyl)pyrimidin-2-amine
CID 68325548
N-[4-[(2R)-morpholin-2-yl]phenyl]-2-(trifluoromethyl)pyrimidin-5-amine
CID 68325553
N-[4-[(2S)-morpholin-2-yl]phenyl]-3-(trifluoromethyl)pyridin-2-amine
CID 68325571

Frequently Asked Questions

What is the IUPAC name of 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine?
The IUPAC name of 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine (CID 118484366) is 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine.
What is the SMILES notation for 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine?
The canonical SMILES for 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine is FC(F)(F)c1ccc(Nc2ccc([C@H]3CNCCO3)nc2)cc1.
What is the InChIKey of 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine?
The InChIKey is CWRDKDSHVOKMNB-OAHLLOKOSA-N. The full InChI is InChI=1S/C16H16F3N3O/c17-16(18,19)11-1-3-12(4-2-11)22-13-5-6-14(21-9-13)15-10-20-7-8-23-15/h1-6,9,15,20,22H,7-8,10H2/t15-/m1/s1.
What are the key properties of 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine?
6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine has a molecular weight of 323.32 g/mol, XLogP of 3.50, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[(2R)-morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine is sourced from PubChem (CID 118484366), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).