6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide

C20H18N6O2 — CID 118664109

IUPAC6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide
SMILESNc1cncc(-c2ccc3cnn(-c4cccc(C(=O)NCCO)n4)c3c2)c1
InChIInChI=1S/C20H18N6O2/c21-16-8-15(10-22-12-16)13-4-5-14-11-24-26(18(14)9-13)19-3-1-2-17(25-19)20(28)23-6-7-27/h1-5,8-12,27H,6-7,21H2,(H,23,28)
InChIKeyPUKSSQCERMKRBQ-UHFFFAOYSA-N
MW374.40 g/mol
LogP1.79
Rot. Bonds5

About 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide

6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide (PubChem CID 118664109) has the molecular formula C20H18N6O2 and a molecular weight of 374.40 g/mol. Its IUPAC name is 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide.

Molecular Properties

Compound Name6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide
PubChem CID118664109
Molecular FormulaC20H18N6O2
Molecular Weight374.40 g/mol
Exact Mass374.15
IUPAC Name6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide
SMILESNc1cncc(-c2ccc3cnn(-c4cccc(C(=O)NCCO)n4)c3c2)c1
InChIInChI=1S/C20H18N6O2/c21-16-8-15(10-22-12-16)13-4-5-14-11-24-26(18(14)9-13)19-3-1-2-17(25-19)20(28)23-6-7-27/h1-5,8-12,27H,6-7,21H2,(H,23,28)
InChIKeyPUKSSQCERMKRBQ-UHFFFAOYSA-N
XLogP1.79
TPSA118.95 Ų
H-Bond Donors3
H-Bond Acceptors7
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500374.40
LogP ≤ 51.79
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 107

Analyze 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

Gsk 343
CID 71268957
Unc1999
CID 72551585
Piperazine, 1-((6-formyl-1H-indol-2-yl)carbonyl)-4-(3-((1-methylethyl)amino)-2-pyridinyl)-
CID 454727
6-cyclopropyl-N-[1-(2-hydroxyethyl)-3-quinolin-2-ylpyrazol-5-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 53328817
N,1-dimethyl-5-[[4-[3-methyl-4-[[(3R)-piperidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide
CID 155925936
6-cyclopropyl-N-[1-(2-hydroxyethyl)-3-phenylpyrazol-5-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 53328252
[5-Amino-8-[4-(1-methylpyrazol-4-yl)phenyl]-1,6-naphthyridin-2-yl]-(3-methoxyazetidin-1-yl)methanone
CID 118660867
(R)-N-(1-Benzyl-1H-pyrazol-4-yl)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxamide
CID 53230343
N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indazole-4-carboxamide
CID 54596764
(13R)-N-[1-[(4-aminophenyl)methyl]pyrazol-4-yl]-13-methyl-10-oxo-1,3,11-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8-tetraene-4-carboxamide
CID 130338820
5-[[4-[4-[[(3R,4R)-3-aminooxan-4-yl]amino]-3-methylpyrazol-1-yl]pyrimidin-2-yl]amino]-N,1-dimethylindazole-3-carboxamide
CID 162645658
5-[[4-[4-[(3-hydroxyazetidin-1-yl)methyl]-3-methylpyrazol-1-yl]pyrimidin-2-yl]amino]-N,1-dimethylindazole-3-carboxamide
CID 162662603

Frequently Asked Questions

What is the IUPAC name of 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide?
The IUPAC name of 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide (CID 118664109) is 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide.
What is the SMILES notation for 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide?
The canonical SMILES for 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide is Nc1cncc(-c2ccc3cnn(-c4cccc(C(=O)NCCO)n4)c3c2)c1.
What is the InChIKey of 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide?
The InChIKey is PUKSSQCERMKRBQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H18N6O2/c21-16-8-15(10-22-12-16)13-4-5-14-11-24-26(18(14)9-13)19-3-1-2-17(25-19)20(28)23-6-7-27/h1-5,8-12,27H,6-7,21H2,(H,23,28).
What are the key properties of 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide?
6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide has a molecular weight of 374.40 g/mol, XLogP of 1.79, 5 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[6-(5-amino-3-pyridinyl)indazol-1-yl]-N-(2-hydroxyethyl)pyridine-2-carboxamide is sourced from PubChem (CID 118664109), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).