About 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine
1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine (PubChem CID 118716249) has the molecular formula C18H14ClN5S
and a molecular weight of 367.87 g/mol. Its IUPAC name is 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine.
Molecular Properties
| Compound Name | 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine |
| PubChem CID | 118716249 |
| Molecular Formula | C18H14ClN5S |
| Molecular Weight | 367.87 g/mol |
| Exact Mass | 367.07 |
| IUPAC Name | 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine |
| SMILES | Cc1ccc2nc(Cl)c(/C=N/n3cc(-c4cccs4)nc3N)cc2c1 |
| InChI | InChI=1S/C18H14ClN5S/c1-11-4-5-14-12(7-11)8-13(17(19)22-14)9-21-24-10-15(23-18(24)20)16-3-2-6-25-16/h2-10H,1H3,(H2,20,23)/b21-9+ |
| InChIKey | IFPSZUREOOUZHV-ZVBGSRNCSA-N |
| XLogP | 4.59 |
| TPSA | 69.09 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 25 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 367.87 |
| LogP ≤ 5 | 4.59 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'imine_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine?
The IUPAC name of 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine (CID 118716249) is 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine.
What is the SMILES notation for 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine?
The canonical SMILES for 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine is Cc1ccc2nc(Cl)c(/C=N/n3cc(-c4cccs4)nc3N)cc2c1.
What is the InChIKey of 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine?
The InChIKey is IFPSZUREOOUZHV-ZVBGSRNCSA-N. The full InChI is InChI=1S/C18H14ClN5S/c1-11-4-5-14-12(7-11)8-13(17(19)22-14)9-21-24-10-15(23-18(24)20)16-3-2-6-25-16/h2-10H,1H3,(H2,20,23)/b21-9+.
What are the key properties of 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine?
1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine has a molecular weight of 367.87 g/mol, XLogP of 4.59, 3 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(E)-(2-chloro-6-methylquinolin-3-yl)methylideneamino]-4-thiophen-2-ylimidazol-2-amine is sourced from PubChem (CID 118716249), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).