About 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane
4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane (PubChem CID 118745047) has the molecular formula C18H21FN4O2
and a molecular weight of 344.39 g/mol. Its IUPAC name is 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane.
Molecular Properties
| Compound Name | 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane |
| PubChem CID | 118745047 |
| Molecular Formula | C18H21FN4O2 |
| Molecular Weight | 344.39 g/mol |
| Exact Mass | 344.16 |
| IUPAC Name | 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane |
| SMILES | Fc1ccc(N2CCOC3(COCCN(c4ncccn4)C3)C2)cc1 |
| InChI | InChI=1S/C18H21FN4O2/c19-15-2-4-16(5-3-15)22-9-11-25-18(12-22)13-23(8-10-24-14-18)17-20-6-1-7-21-17/h1-7H,8-14H2 |
| InChIKey | NVSSWVGHLKUGHR-UHFFFAOYSA-N |
| XLogP | 1.73 |
| TPSA | 50.72 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 25 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 344.39 |
| LogP ≤ 5 | 1.73 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane?
The IUPAC name of 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane (CID 118745047) is 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane.
What is the SMILES notation for 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane?
The canonical SMILES for 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane is Fc1ccc(N2CCOC3(COCCN(c4ncccn4)C3)C2)cc1.
What is the InChIKey of 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane?
The InChIKey is NVSSWVGHLKUGHR-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H21FN4O2/c19-15-2-4-16(5-3-15)22-9-11-25-18(12-22)13-23(8-10-24-14-18)17-20-6-1-7-21-17/h1-7H,8-14H2.
What are the key properties of 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane?
4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane has a molecular weight of 344.39 g/mol, XLogP of 1.73, 2 rotatable bonds, 0 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(4-fluorophenyl)-8-pyrimidin-2-yl-1,11-dioxa-4,8-diazaspiro[5.6]dodecane is sourced from PubChem (CID 118745047), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).