6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide

C8H8F2N2O2 — CID 118837404

IUPAC6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide
SMILESCc1nc(C(F)F)c(O)cc1C(N)=O
InChIInChI=1S/C8H8F2N2O2/c1-3-4(8(11)14)2-5(13)6(12-3)7(9)10/h2,7,13H,1H3,(H2,11,14)
InChIKeyXCVOBTFNYIJZKP-UHFFFAOYSA-N
MW202.16 g/mol
LogP1.13
Rot. Bonds2

About 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide

6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide (PubChem CID 118837404) has the molecular formula C8H8F2N2O2 and a molecular weight of 202.16 g/mol. Its IUPAC name is 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide.

Molecular Properties

Compound Name6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide
PubChem CID118837404
Molecular FormulaC8H8F2N2O2
Molecular Weight202.16 g/mol
Exact Mass202.06
IUPAC Name6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide
SMILESCc1nc(C(F)F)c(O)cc1C(N)=O
InChIInChI=1S/C8H8F2N2O2/c1-3-4(8(11)14)2-5(13)6(12-3)7(9)10/h2,7,13H,1H3,(H2,11,14)
InChIKeyXCVOBTFNYIJZKP-UHFFFAOYSA-N
XLogP1.13
TPSA76.21 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500202.16
LogP ≤ 51.13
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-(difluoromethyl)-5-hydroxy-6-iodopyridine-3-carboxamide
CID 118809374
ethyl 2-[6-(difluoromethyl)-5-hydroxy-2-methyl-3-pyridinyl]acetate
CID 133102899
6-(difluoromethyl)-5-hydroxy-3-methylpyridine-2-carboxylic acid
CID 118831600
6-(difluoromethyl)-2-fluoro-5-methylpyridine-3-carboxamide
CID 118814860
ethyl 2-bromo-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylate
CID 134684348
methyl 2-[6-(difluoromethyl)-5-hydroxy-2-methyl-3-pyridinyl]acetate
CID 133103275
6-amino-2-(difluoromethyl)-3-hydroxypyridine-4-carboxamide
CID 130105130
5-amino-6-(difluoromethyl)-3-methylpyridine-2-carboxamide
CID 130106784
ethyl 3-bromo-6-(difluoromethyl)-5-hydroxypyridine-2-carboxylate
CID 134670794
6-(difluoromethyl)-5-hydroxy-4-methylpyridine-3-carboxamide
CID 130084161
2-(difluoromethyl)-3-hydroxy-6-iodopyridine-4-carboxamide
CID 118837184
2-(difluoromethyl)-5-iodo-6-methylpyridine-3-carbonyl chloride
CID 118849139

Frequently Asked Questions

What is the IUPAC name of 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide?
The IUPAC name of 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide (CID 118837404) is 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide.
What is the SMILES notation for 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide?
The canonical SMILES for 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide is Cc1nc(C(F)F)c(O)cc1C(N)=O.
What is the InChIKey of 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide?
The InChIKey is XCVOBTFNYIJZKP-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H8F2N2O2/c1-3-4(8(11)14)2-5(13)6(12-3)7(9)10/h2,7,13H,1H3,(H2,11,14).
What are the key properties of 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide?
6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide has a molecular weight of 202.16 g/mol, XLogP of 1.13, 2 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide is sourced from PubChem (CID 118837404), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).