About 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline
2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline (PubChem CID 118890842) has the molecular formula C22H21FN6O
and a molecular weight of 404.45 g/mol. Its IUPAC name is 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline.
Molecular Properties
| Compound Name | 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline |
| PubChem CID | 118890842 |
| Molecular Formula | C22H21FN6O |
| Molecular Weight | 404.45 g/mol |
| Exact Mass | 404.18 |
| IUPAC Name | 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline |
| SMILES | C[C@@H]1COCCN1c1cc(-c2cccc(F)c2N)c2ccnc(-c3ccn[nH]3)c2n1 |
| InChI | InChI=1S/C22H21FN6O/c1-13-12-30-10-9-29(13)19-11-16(14-3-2-4-17(23)20(14)24)15-5-7-25-22(21(15)27-19)18-6-8-26-28-18/h2-8,11,13H,9-10,12,24H2,1H3,(H,26,28)/t13-/m1/s1 |
| InChIKey | XDWMVLMBPVLMJU-CYBMUJFWSA-N |
| XLogP | 3.63 |
| TPSA | 92.95 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 404.45 |
| LogP ≤ 5 | 3.63 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'aniline', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline?
The IUPAC name of 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline (CID 118890842) is 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline.
What is the SMILES notation for 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline?
The canonical SMILES for 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline is C[C@@H]1COCCN1c1cc(-c2cccc(F)c2N)c2ccnc(-c3ccn[nH]3)c2n1.
What is the InChIKey of 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline?
The InChIKey is XDWMVLMBPVLMJU-CYBMUJFWSA-N. The full InChI is InChI=1S/C22H21FN6O/c1-13-12-30-10-9-29(13)19-11-16(14-3-2-4-17(23)20(14)24)15-5-7-25-22(21(15)27-19)18-6-8-26-28-18/h2-8,11,13H,9-10,12,24H2,1H3,(H,26,28)/t13-/m1/s1.
What are the key properties of 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline?
2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline has a molecular weight of 404.45 g/mol, XLogP of 3.63, 3 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-fluoro-6-[2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]aniline is sourced from PubChem (CID 118890842), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).