About N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide
N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide (PubChem CID 121304926) has the molecular formula C22H18FN7O2
and a molecular weight of 431.43 g/mol. Its IUPAC name is N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide.
Molecular Properties
| Compound Name | N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide |
| PubChem CID | 121304926 |
| Molecular Formula | C22H18FN7O2 |
| Molecular Weight | 431.43 g/mol |
| Exact Mass | 431.15 |
| IUPAC Name | N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide |
| SMILES | Nc1ccc(-c2ccnc(N(CNC(=O)c3cccc(F)c3O)c3cnccn3)c2)cn1 |
| InChI | InChI=1S/C22H18FN7O2/c23-17-3-1-2-16(21(17)31)22(32)29-13-30(20-12-25-8-9-27-20)19-10-14(6-7-26-19)15-4-5-18(24)28-11-15/h1-12,31H,13H2,(H2,24,28)(H,29,32) |
| InChIKey | WDCIKZMYLUHCKT-UHFFFAOYSA-N |
| XLogP | 2.89 |
| TPSA | 130.15 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 431.43 |
| LogP ≤ 5 | 2.89 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 8 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'dyes5A(27)', 'substructure': 'N/A'}, {'alert_name': 'het-C-het_not_in_ring', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide?
The IUPAC name of N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide (CID 121304926) is N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide.
What is the SMILES notation for N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide?
The canonical SMILES for N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide is Nc1ccc(-c2ccnc(N(CNC(=O)c3cccc(F)c3O)c3cnccn3)c2)cn1.
What is the InChIKey of N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide?
The InChIKey is WDCIKZMYLUHCKT-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H18FN7O2/c23-17-3-1-2-16(21(17)31)22(32)29-13-30(20-12-25-8-9-27-20)19-10-14(6-7-26-19)15-4-5-18(24)28-11-15/h1-12,31H,13H2,(H2,24,28)(H,29,32).
What are the key properties of N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide?
N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide has a molecular weight of 431.43 g/mol, XLogP of 2.89, 6 rotatable bonds, 3 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[[4-(6-amino-3-pyridinyl)-2-pyridinyl]-pyrazin-2-ylamino]methyl]-3-fluoro-2-hydroxybenzamide is sourced from PubChem (CID 121304926), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).