About 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide
1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide (PubChem CID 121333930) has the molecular formula C26H18ClFN4O3S
and a molecular weight of 520.97 g/mol. Its IUPAC name is 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide.
Molecular Properties
| Compound Name | 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide |
| PubChem CID | 121333930 |
| Molecular Formula | C26H18ClFN4O3S |
| Molecular Weight | 520.97 g/mol |
| Exact Mass | 520.08 |
| IUPAC Name | 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide |
| SMILES | COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1nccc2cc(S(=O)(=O)Nc3ncccn3)ccc12 |
| InChI | InChI=1S/C26H18ClFN4O3S/c1-35-24-15-21(16-4-2-5-18(28)12-16)23(27)14-22(24)25-20-7-6-19(13-17(20)8-11-29-25)36(33,34)32-26-30-9-3-10-31-26/h2-15H,1H3,(H,30,31,32) |
| InChIKey | DUWRTDJSNRFMAI-UHFFFAOYSA-N |
| XLogP | 5.96 |
| TPSA | 94.07 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 36 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 520.97 |
| LogP ≤ 5 | 5.96 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide?
The IUPAC name of 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide (CID 121333930) is 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide.
What is the SMILES notation for 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide?
The canonical SMILES for 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide is COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1nccc2cc(S(=O)(=O)Nc3ncccn3)ccc12.
What is the InChIKey of 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide?
The InChIKey is DUWRTDJSNRFMAI-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H18ClFN4O3S/c1-35-24-15-21(16-4-2-5-18(28)12-16)23(27)14-22(24)25-20-7-6-19(13-17(20)8-11-29-25)36(33,34)32-26-30-9-3-10-31-26/h2-15H,1H3,(H,30,31,32).
What are the key properties of 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide?
1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide has a molecular weight of 520.97 g/mol, XLogP of 5.96, 6 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[5-chloro-4-(3-fluorophenyl)-2-methoxyphenyl]-N-pyrimidin-2-ylisoquinoline-6-sulfonamide is sourced from PubChem (CID 121333930), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).