About (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone
(2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone (PubChem CID 121344811) has the molecular formula C22H30N4O3
and a molecular weight of 398.51 g/mol. Its IUPAC name is (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone.
Molecular Properties
| Compound Name | (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone |
| PubChem CID | 121344811 |
| Molecular Formula | C22H30N4O3 |
| Molecular Weight | 398.51 g/mol |
| Exact Mass | 398.23 |
| IUPAC Name | (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone |
| SMILES | COc1ccc(C(=O)N2C[C@H](n3cc(C(C)(C)O)cn3)CC[C@H]2C)c(C2CC2)n1 |
| InChI | InChI=1S/C22H30N4O3/c1-14-5-8-17(26-12-16(11-23-26)22(2,3)28)13-25(14)21(27)18-9-10-19(29-4)24-20(18)15-6-7-15/h9-12,14-15,17,28H,5-8,13H2,1-4H3/t14-,17-/m1/s1 |
| InChIKey | FIAXYYWAVURXTQ-RHSMWYFYSA-N |
| XLogP | 3.26 |
| TPSA | 80.48 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 398.51 |
| LogP ≤ 5 | 3.26 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone?
The IUPAC name of (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone (CID 121344811) is (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone.
What is the SMILES notation for (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone?
The canonical SMILES for (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone is COc1ccc(C(=O)N2C[C@H](n3cc(C(C)(C)O)cn3)CC[C@H]2C)c(C2CC2)n1.
What is the InChIKey of (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone?
The InChIKey is FIAXYYWAVURXTQ-RHSMWYFYSA-N. The full InChI is InChI=1S/C22H30N4O3/c1-14-5-8-17(26-12-16(11-23-26)22(2,3)28)13-25(14)21(27)18-9-10-19(29-4)24-20(18)15-6-7-15/h9-12,14-15,17,28H,5-8,13H2,1-4H3/t14-,17-/m1/s1.
What are the key properties of (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone?
(2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone has a molecular weight of 398.51 g/mol, XLogP of 3.26, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for (2-cyclopropyl-6-methoxy-3-pyridinyl)-[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)pyrazol-1-yl]-2-methylpiperidin-1-yl]methanone is sourced from PubChem (CID 121344811), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).