5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione

C19H23ClF2N4O4 — CID 121437890

IUPAC5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione
SMILESCOCC1(CC(C)C(=O)N2CCN(c3cc(F)c(Cl)c(F)c3)CC2)NC(=O)NC1=O
InChIInChI=1S/C19H23ClF2N4O4/c1-11(9-19(10-30-2)17(28)23-18(29)24-19)16(27)26-5-3-25(4-6-26)12-7-13(21)15(20)14(22)8-12/h7-8,11H,3-6,9-10H2,1-2H3,(H2,23,24,28,29)
InChIKeyUHKJKGYIHRIXMQ-UHFFFAOYSA-N
MW444.87 g/mol
LogP1.52
Rot. Bonds6

About 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione

5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione (PubChem CID 121437890) has the molecular formula C19H23ClF2N4O4 and a molecular weight of 444.87 g/mol. Its IUPAC name is 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione.

Molecular Properties

Compound Name5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione
PubChem CID121437890
Molecular FormulaC19H23ClF2N4O4
Molecular Weight444.87 g/mol
Exact Mass444.14
IUPAC Name5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione
SMILESCOCC1(CC(C)C(=O)N2CCN(c3cc(F)c(Cl)c(F)c3)CC2)NC(=O)NC1=O
InChIInChI=1S/C19H23ClF2N4O4/c1-11(9-19(10-30-2)17(28)23-18(29)24-19)16(27)26-5-3-25(4-6-26)12-7-13(21)15(20)14(22)8-12/h7-8,11H,3-6,9-10H2,1-2H3,(H2,23,24,28,29)
InChIKeyUHKJKGYIHRIXMQ-UHFFFAOYSA-N
XLogP1.52
TPSA90.98 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds6
Heavy Atoms30
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500444.87
LogP ≤ 51.52
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'halogenated_ring_2', 'substructure': 'N/A'}, {'alert_name': 'hydantoin', 'substructure': 'N/A'}

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Related Compounds

5-[3-[4-(3,5-Dichlorophenyl)piperazin-1-yl]-2-(hydroxymethyl)-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437747
5-[3-[4-(3,5-Dichlorophenyl)piperazin-1-yl]-2-(methoxymethyl)-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437888
5-[3-[4-(4-Chloro-3-fluorophenyl)piperazin-1-yl]-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437587
5-[3-[4-(3,4-Difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione
CID 121437593
5-[3-[(3S)-4-(3-chloro-4-fluorophenyl)-3-methylpiperazin-1-yl]-2-(methoxymethyl)-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437615
5-[3-[4-(3-Chloro-5-fluorophenyl)piperazin-1-yl]-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437669
5-[3-[(3S)-4-(3-chloro-4-fluorophenyl)-3-methylpiperazin-1-yl]-2-methyl-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437692
5-[3-[(3S)-4-(3-fluorophenyl)-3-methylpiperazin-1-yl]-2-(methoxymethyl)-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437714
5-[3-[(3S)-4-(4-chloro-3,5-difluorophenyl)-3-methylpiperazin-1-yl]-2-methyl-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437811
5-[3-[(3S)-4-(3-chloro-5-fluorophenyl)-3-methylpiperazin-1-yl]-2-(methoxymethyl)-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437836
5-[3-[(3S)-4-(3-chloro-5-fluorophenyl)-3-methylpiperazin-1-yl]-2-methyl-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437879
(5R)-5-[(2S)-3-[(3S)-4-(3-chloro-4-fluorophenyl)-3-methylpiperazin-1-yl]-2-methyl-3-oxopropyl]-5-methylimidazolidine-2,4-dione
CID 121437902

Frequently Asked Questions

What is the IUPAC name of 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione?
The IUPAC name of 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione (CID 121437890) is 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione.
What is the SMILES notation for 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione?
The canonical SMILES for 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione is COCC1(CC(C)C(=O)N2CCN(c3cc(F)c(Cl)c(F)c3)CC2)NC(=O)NC1=O.
What is the InChIKey of 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione?
The InChIKey is UHKJKGYIHRIXMQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H23ClF2N4O4/c1-11(9-19(10-30-2)17(28)23-18(29)24-19)16(27)26-5-3-25(4-6-26)12-7-13(21)15(20)14(22)8-12/h7-8,11H,3-6,9-10H2,1-2H3,(H2,23,24,28,29).
What are the key properties of 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione?
5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione has a molecular weight of 444.87 g/mol, XLogP of 1.52, 6 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-[4-(4-chloro-3,5-difluorophenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]-5-(methoxymethyl)imidazolidine-2,4-dione is sourced from PubChem (CID 121437890), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).