(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide

C18H22N2O3 — CID 122624589

IUPAC(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide
SMILESO=C(c1ccc2c(c1)CC[C@@]1(CCCNC1=O)C2)N(O)C1CC1
InChIInChI=1S/C18H22N2O3/c21-16(20(23)15-4-5-15)13-2-3-14-11-18(8-6-12(14)10-13)7-1-9-19-17(18)22/h2-3,10,15,23H,1,4-9,11H2,(H,19,22)/t18-/m0/s1
InChIKeyAAIXAJBDKXHSKH-SFHVURJKSA-N
MW314.38 g/mol
LogP2.07
Rot. Bonds2

About (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide

(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide (PubChem CID 122624589) has the molecular formula C18H22N2O3 and a molecular weight of 314.38 g/mol. Its IUPAC name is (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide.

Molecular Properties

Compound Name(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide
PubChem CID122624589
Molecular FormulaC18H22N2O3
Molecular Weight314.38 g/mol
Exact Mass314.16
IUPAC Name(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide
SMILESO=C(c1ccc2c(c1)CC[C@@]1(CCCNC1=O)C2)N(O)C1CC1
InChIInChI=1S/C18H22N2O3/c21-16(20(23)15-4-5-15)13-2-3-14-11-18(8-6-12(14)10-13)7-1-9-19-17(18)22/h2-3,10,15,23H,1,4-9,11H2,(H,19,22)/t18-/m0/s1
InChIKeyAAIXAJBDKXHSKH-SFHVURJKSA-N
XLogP2.07
TPSA69.64 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500314.38
LogP ≤ 52.07
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide with MolForge

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Related Compounds

(6R)-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxylic acid
CID 122616298
7-acetylspiro[2,4-dihydro-1H-naphthalene-3,3'-pyrrolidine]-2'-one
CID 122634837
(6R)-N-hydroxy-N-(6-methyl-3-pyridinyl)-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624547
2'-oxo-N-[2-(4-phenylpiperidin-1-yl)ethyl]spiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide
CID 143201235
(6R)-N-(2-cyanophenyl)-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624691
(6S)-N-[6-(dimethylamino)-3-pyridinyl]-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624614
(6S)-N-hydroxy-N-(4-methyl-3-pyridinyl)-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624611
(6R)-N-hydroxy-2'-oxo-N-quinolin-3-ylspiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624596
(6R)-N-hydroxy-N-[(4-methylsulfonylphenyl)methyl]-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-pyrrolidine]-2-carboxamide
CID 122624532
(7S)-N-hydroxy-2'-oxo-N-pyridin-3-ylspiro[6,8-dihydro-5H-naphthalene-7,3'-pyrrolidine]-2-carboxamide
CID 122622984
N-[4-(4-methyl-2-oxopiperazin-1-yl)phenyl]-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide
CID 143201220
(7S)-N-hydroxy-N-[(2-methylphenyl)methyl]-2'-oxospiro[6,8-dihydro-5H-naphthalene-7,3'-pyrrolidine]-2-carboxamide
CID 122623083

Frequently Asked Questions

What is the IUPAC name of (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide?
The IUPAC name of (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide (CID 122624589) is (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide.
What is the SMILES notation for (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide?
The canonical SMILES for (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide is O=C(c1ccc2c(c1)CC[C@@]1(CCCNC1=O)C2)N(O)C1CC1.
What is the InChIKey of (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide?
The InChIKey is AAIXAJBDKXHSKH-SFHVURJKSA-N. The full InChI is InChI=1S/C18H22N2O3/c21-16(20(23)15-4-5-15)13-2-3-14-11-18(8-6-12(14)10-13)7-1-9-19-17(18)22/h2-3,10,15,23H,1,4-9,11H2,(H,19,22)/t18-/m0/s1.
What are the key properties of (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide?
(6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide has a molecular weight of 314.38 g/mol, XLogP of 2.07, 2 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (6R)-N-cyclopropyl-N-hydroxy-2'-oxospiro[7,8-dihydro-5H-naphthalene-6,3'-piperidine]-2-carboxamide is sourced from PubChem (CID 122624589), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).