About [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone
[5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone (PubChem CID 122652927) has the molecular formula C19H12ClF2N3O3S
and a molecular weight of 435.84 g/mol. Its IUPAC name is [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone.
Molecular Properties
| Compound Name | [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone |
| PubChem CID | 122652927 |
| Molecular Formula | C19H12ClF2N3O3S |
| Molecular Weight | 435.84 g/mol |
| Exact Mass | 435.03 |
| IUPAC Name | [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone |
| SMILES | COc1c(Cl)cc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1CN=[N+]=[N-] |
| InChI | InChI=1S/C19H12ClF2N3O3S/c1-28-19-10(8-24-25-23)6-9(7-11(19)20)14-4-5-15(29-14)18(27)16-12(21)2-3-13(26)17(16)22/h2-7,26H,8H2,1H3 |
| InChIKey | FVJOEIWTJIZFPR-UHFFFAOYSA-N |
| XLogP | 6.10 |
| TPSA | 95.29 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 435.84 |
| LogP ≤ 5 | 6.10 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'azo_A(324)', 'substructure': 'N/A'}, {'alert_name': 'Azido_group', 'substructure': 'N/A'}, {'alert_name': 'diazo_group', 'substructure': 'N/A'}, {'alert_name': 'quaternary_nitrogen_3', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone?
The IUPAC name of [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone (CID 122652927) is [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone.
What is the SMILES notation for [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone?
The canonical SMILES for [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone is COc1c(Cl)cc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1CN=[N+]=[N-].
What is the InChIKey of [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone?
The InChIKey is FVJOEIWTJIZFPR-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H12ClF2N3O3S/c1-28-19-10(8-24-25-23)6-9(7-11(19)20)14-4-5-15(29-14)18(27)16-12(21)2-3-13(26)17(16)22/h2-7,26H,8H2,1H3.
What are the key properties of [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone?
[5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone has a molecular weight of 435.84 g/mol, XLogP of 6.10, 6 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for [5-[3-(azidomethyl)-5-chloro-4-methoxyphenyl]thiophen-2-yl]-(2,6-difluoro-3-hydroxyphenyl)methanone is sourced from PubChem (CID 122652927), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).