3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine

C61H73N23S3 — CID 123144823

About 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine

3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine (PubChem CID 123144823) has the molecular formula C61H73N23S3 and a molecular weight of 1224.62 g/mol. Its IUPAC name is 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine.

Molecular Properties

• Compound Name: 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine
• PubChem CID: 123144823
• Molecular Formula: C61H73N23S3
• Molecular Weight: 1224.62 g/mol
• Exact Mass: 1223.56
• IUPAC Name: 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine
• SMILES: Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CCN3CCCCC3)ns2)n1.Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCCCC3(C)C)ns2)n1.Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2ccc(CN3CCCCC3)s2)n1
• InChI: InChI=1S/C21H26N8S.C20H24N8S.C20H23N7S/c1-14-12-29-17(15-9-23-24-10-15)11-22-20(29)19(25-14)26-18-8-16(27-30-18)13-28-7-5-4-6-21(28,2)3;1-14-13-28-17(15-10-22-23-11-15)12-21-20(28)19(24-14)25-18-9-16(26-29-18)5-8-27-6-3-2-4-7-27;1-14-12-27-17(15-9-22-23-10-15)11-21-20(27)19(24-14)25-18-6-5-16(28-18)13-26-7-3-2-4-8-26/h8-12H,4-7,13H2,1-3H3,(H,23,24)(H,25,26);9-13H,2-8H2,1H3,(H,22,23)(H,24,25);5-6,9-12H,2-4,7-8,13H2,1H3,(H,22,23)(H,24,25)
• InChIKey: JJKSJNSCEQCANG-UHFFFAOYSA-N
• XLogP: 12.27
• TPSA: 248.20 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 23
• Rotatable Bonds: 16
• Heavy Atoms: 87
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1224.62
LogP ≤ 5	12.27
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	23

Frequently Asked Questions

What is the IUPAC name of 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine?

The IUPAC name of 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine (CID 123144823) is 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine.

What is the SMILES notation for 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine?

The canonical SMILES for 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine is Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CCN3CCCCC3)ns2)n1.Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCCCC3(C)C)ns2)n1.Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2ccc(CN3CCCCC3)s2)n1.

What is the InChIKey of 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine?

The InChIKey is JJKSJNSCEQCANG-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H26N8S.C20H24N8S.C20H23N7S/c1-14-12-29-17(15-9-23-24-10-15)11-22-20(29)19(25-14)26-18-8-16(27-30-18)13-28-7-5-4-6-21(28,2)3;1-14-13-28-17(15-10-22-23-11-15)12-21-20(28)19(24-14)25-18-9-16(26-29-18)5-8-27-6-3-2-4-7-27;1-14-12-27-17(15-9-22-23-10-15)11-21-20(27)19(24-14)25-18-6-5-16(28-18)13-26-7-3-2-4-8-26/h8-12H,4-7,13H2,1-3H3,(H,23,24)(H,25,26);9-13H,2-8H2,1H3,(H,22,23)(H,24,25);5-6,9-12H,2-4,7-8,13H2,1H3,(H,22,23)(H,24,25).

What are the key properties of 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine?

3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine has a molecular weight of 1224.62 g/mol, XLogP of 12.27, 16 rotatable bonds, 6 hydrogen bond donors, and 23 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[(2,2-dimethylpiperidin-1-yl)methyl]-N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;6-methyl-N-[5-(piperidin-1-ylmethyl)thiophen-2-yl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(2-piperidin-1-ylethyl)-1,2-thiazol-5-amine is sourced from PubChem (CID 123144823), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).