(8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane

C18H24N4O2S — CID 124803188

About (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane

(8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane (PubChem CID 124803188) has the molecular formula C18H24N4O2S and a molecular weight of 360.48 g/mol. Its IUPAC name is (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane.

Molecular Properties

• Compound Name: (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane
• PubChem CID: 124803188
• Molecular Formula: C18H24N4O2S
• Molecular Weight: 360.48 g/mol
• Exact Mass: 360.16
• IUPAC Name: (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane
• SMILES: Cc1csc(CN2CC3(C[C@@H](CCOc4cnccn4)CCO3)C2)n1
• InChI: InChI=1S/C18H24N4O2S/c1-14-11-25-17(21-14)10-22-12-18(13-22)8-15(3-7-24-18)2-6-23-16-9-19-4-5-20-16/h4-5,9,11,15H,2-3,6-8,10,12-13H2,1H3/t15-/m0/s1
• InChIKey: OXUOJMTXQBVJEM-HNNXBMFYSA-N
• XLogP: 2.69
• TPSA: 60.37 Ų
• H-Bond Acceptors: 7
• Rotatable Bonds: 6
• Heavy Atoms: 25
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	360.48
LogP ≤ 5	2.69
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane?

The IUPAC name of (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane (CID 124803188) is (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane.

What is the SMILES notation for (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane?

The canonical SMILES for (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane is Cc1csc(CN2CC3(C[C@@H](CCOc4cnccn4)CCO3)C2)n1.

What is the InChIKey of (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane?

The InChIKey is OXUOJMTXQBVJEM-HNNXBMFYSA-N. The full InChI is InChI=1S/C18H24N4O2S/c1-14-11-25-17(21-14)10-22-12-18(13-22)8-15(3-7-24-18)2-6-23-16-9-19-4-5-20-16/h4-5,9,11,15H,2-3,6-8,10,12-13H2,1H3/t15-/m0/s1.

What are the key properties of (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane?

(8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane has a molecular weight of 360.48 g/mol, XLogP of 2.69, 6 rotatable bonds, 0 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for (8R)-2-[(4-methyl-1,3-thiazol-2-yl)methyl]-8-(2-pyrazin-2-yloxyethyl)-5-oxa-2-azaspiro[3.5]nonane is sourced from PubChem (CID 124803188), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).