(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol

C14H16F3N5O — CID 124884128

IUPAC(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol
SMILESO[C@@H](c1ncc[nH]1)C1CCN(c2nccc(C(F)(F)F)n2)CC1
InChIInChI=1S/C14H16F3N5O/c15-14(16,17)10-1-4-20-13(21-10)22-7-2-9(3-8-22)11(23)12-18-5-6-19-12/h1,4-6,9,11,23H,2-3,7-8H2,(H,18,19)/t11-/m1/s1
InChIKeyWVQXICDIXPHFTB-LLVKDONJSA-N
MW327.31 g/mol
LogP2.17
Rot. Bonds3

About (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol

(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol (PubChem CID 124884128) has the molecular formula C14H16F3N5O and a molecular weight of 327.31 g/mol. Its IUPAC name is (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol.

Molecular Properties

Compound Name(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol
PubChem CID124884128
Molecular FormulaC14H16F3N5O
Molecular Weight327.31 g/mol
Exact Mass327.13
IUPAC Name(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol
SMILESO[C@@H](c1ncc[nH]1)C1CCN(c2nccc(C(F)(F)F)n2)CC1
InChIInChI=1S/C14H16F3N5O/c15-14(16,17)10-1-4-20-13(21-10)22-7-2-9(3-8-22)11(23)12-18-5-6-19-12/h1,4-6,9,11,23H,2-3,7-8H2,(H,18,19)/t11-/m1/s1
InChIKeyWVQXICDIXPHFTB-LLVKDONJSA-N
XLogP2.17
TPSA77.93 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500327.31
LogP ≤ 52.17
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Analyze (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol with MolForge

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Related Compounds

(1-methyl-1H-imidazol-2-yl){1-[4-(3,3,3-trifluoropropyl)pyrimidin-2-yl]piperidin-4-yl}methanol
CID 56864248
(S)-[1-(5-bromopyrimidin-4-yl)piperidin-4-yl]-(1H-imidazol-2-yl)methanol
CID 124883293
N-[(1-ethyl-1H-imidazol-2-yl)(oxan-4-yl)methyl]-4-(trifluoromethyl)pyrimidin-2-amine
CID 128979362
Imidazolylpyrimidinemethanol
CID 129780694
1-(1-methyl-1H-imidazol-2-yl)-2-{[4-(trifluoromethyl)-2-pyrimidinyl]amino}ethanol
CID 45931872
1,1,1-Trifluoro-2-(1-methylimidazol-2-yl)-4-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]butan-2-ol
CID 47034311
(2S)-1,1,1-trifluoro-2-(1-methylimidazol-2-yl)-4-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]butan-2-ol
CID 52224846
(2R)-1,1,1-trifluoro-2-(1-methylimidazol-2-yl)-4-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]butan-2-ol
CID 52224847
2-[4-[[[4-(Trifluoromethyl)pyrimidin-2-yl]amino]methyl]piperidin-1-yl]ethanol
CID 53560966
1-(4-Methylpiperidin-1-yl)-3-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]propan-2-ol
CID 53622919
4-methyl-2-[4-[5-(trifluoromethyl)-1H-imidazol-2-yl]piperidin-1-yl]pyrimidine
CID 71996187
(2R)-1-(4-methylpiperidin-1-yl)-3-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]propan-2-ol
CID 95186920

Frequently Asked Questions

What is the IUPAC name of (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol?
The IUPAC name of (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol (CID 124884128) is (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol.
What is the SMILES notation for (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol?
The canonical SMILES for (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol is O[C@@H](c1ncc[nH]1)C1CCN(c2nccc(C(F)(F)F)n2)CC1.
What is the InChIKey of (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol?
The InChIKey is WVQXICDIXPHFTB-LLVKDONJSA-N. The full InChI is InChI=1S/C14H16F3N5O/c15-14(16,17)10-1-4-20-13(21-10)22-7-2-9(3-8-22)11(23)12-18-5-6-19-12/h1,4-6,9,11,23H,2-3,7-8H2,(H,18,19)/t11-/m1/s1.
What are the key properties of (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol?
(R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol has a molecular weight of 327.31 g/mol, XLogP of 2.17, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for (R)-1H-imidazol-2-yl-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanol is sourced from PubChem (CID 124884128), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).