2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide

C20H27N5O — CID 124910184

IUPAC2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide
SMILESC[C@@H]1c2nc(CC(=O)NCc3cccnc3)cn2CCN1CC1CCC1
InChIInChI=1S/C20H27N5O/c1-15-20-23-18(10-19(26)22-12-17-6-3-7-21-11-17)14-25(20)9-8-24(15)13-16-4-2-5-16/h3,6-7,11,14-16H,2,4-5,8-10,12-13H2,1H3,(H,22,26)/t15-/m1/s1
InChIKeyHSBRWTGSROPGCJ-OAHLLOKOSA-N
MW353.47 g/mol
LogP2.31
Rot. Bonds6

About 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide

2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide (PubChem CID 124910184) has the molecular formula C20H27N5O and a molecular weight of 353.47 g/mol. Its IUPAC name is 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide.

Molecular Properties

Compound Name2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide
PubChem CID124910184
Molecular FormulaC20H27N5O
Molecular Weight353.47 g/mol
Exact Mass353.22
IUPAC Name2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide
SMILESC[C@@H]1c2nc(CC(=O)NCc3cccnc3)cn2CCN1CC1CCC1
InChIInChI=1S/C20H27N5O/c1-15-20-23-18(10-19(26)22-12-17-6-3-7-21-11-17)14-25(20)9-8-24(15)13-16-4-2-5-16/h3,6-7,11,14-16H,2,4-5,8-10,12-13H2,1H3,(H,22,26)/t15-/m1/s1
InChIKeyHSBRWTGSROPGCJ-OAHLLOKOSA-N
XLogP2.31
TPSA63.05 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds6
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500353.47
LogP ≤ 52.31
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide with MolForge

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Related Compounds

2-[7-(cyclobutanecarbonyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide
CID 131695245
2-[7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-[(5-methylpyrazin-2-yl)methyl]acetamide
CID 133143017
2-[7-(cyclohexylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N,N-dimethylacetamide
CID 133142390
2-[8-methyl-7-(pyridin-2-ylmethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-pyridin-3-ylacetamide
CID 133140620
(8S)-8-methyl-N-propan-2-yl-7-(pyridin-3-ylmethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide
CID 124809087
2-(7-cyclobutyl-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl)-N-(furan-2-ylmethyl)acetamide
CID 133140587
2-[8-methyl-7-(oxan-4-yl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-pyridin-3-ylacetamide
CID 133143135
8-methyl-N-propan-2-yl-7-(pyridin-3-ylmethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide;bis(2,2,2-trifluoroacetic acid)
CID 155862125
2-imidazo[2,1-b][1,3]thiazol-6-yl-N-(pyridin-3-ylmethyl)acetamide
CID 35511835
N-(cyclopropylmethyl)-2-[7-(1H-indole-3-carbonyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]acetamide
CID 131694015
N-(pyridin-3-ylmethyl)-2-(2-pyridin-3-yl-1,3-thiazol-4-yl)acetamide
CID 39084438
2-[(8R)-7-cyclopentyl-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-cyclopropylacetamide
CID 124910267

Frequently Asked Questions

What is the IUPAC name of 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide?
The IUPAC name of 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide (CID 124910184) is 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide.
What is the SMILES notation for 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide?
The canonical SMILES for 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide is C[C@@H]1c2nc(CC(=O)NCc3cccnc3)cn2CCN1CC1CCC1.
What is the InChIKey of 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide?
The InChIKey is HSBRWTGSROPGCJ-OAHLLOKOSA-N. The full InChI is InChI=1S/C20H27N5O/c1-15-20-23-18(10-19(26)22-12-17-6-3-7-21-11-17)14-25(20)9-8-24(15)13-16-4-2-5-16/h3,6-7,11,14-16H,2,4-5,8-10,12-13H2,1H3,(H,22,26)/t15-/m1/s1.
What are the key properties of 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide?
2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide has a molecular weight of 353.47 g/mol, XLogP of 2.31, 6 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(8R)-7-(cyclobutylmethyl)-8-methyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-N-(pyridin-3-ylmethyl)acetamide is sourced from PubChem (CID 124910184), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).