About 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one
1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one (PubChem CID 126891006) has the molecular formula C20H26F3N5O
and a molecular weight of 409.46 g/mol. Its IUPAC name is 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one.
Molecular Properties
| Compound Name | 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one |
| PubChem CID | 126891006 |
| Molecular Formula | C20H26F3N5O |
| Molecular Weight | 409.46 g/mol |
| Exact Mass | 409.21 |
| IUPAC Name | 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one |
| SMILES | O=C1C(N2CCC(N(c3cc(C(F)(F)F)ncn3)C3CC3)CC2)CCN1C1CC1 |
| InChI | InChI=1S/C20H26F3N5O/c21-20(22,23)17-11-18(25-12-24-17)28(14-3-4-14)15-5-8-26(9-6-15)16-7-10-27(19(16)29)13-1-2-13/h11-16H,1-10H2 |
| InChIKey | MXZGTCRXYMSKOX-UHFFFAOYSA-N |
| XLogP | 2.69 |
| TPSA | 52.57 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 409.46 |
| LogP ≤ 5 | 2.69 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one?
The IUPAC name of 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one (CID 126891006) is 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one.
What is the SMILES notation for 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one?
The canonical SMILES for 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one is O=C1C(N2CCC(N(c3cc(C(F)(F)F)ncn3)C3CC3)CC2)CCN1C1CC1.
What is the InChIKey of 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one?
The InChIKey is MXZGTCRXYMSKOX-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H26F3N5O/c21-20(22,23)17-11-18(25-12-24-17)28(14-3-4-14)15-5-8-26(9-6-15)16-7-10-27(19(16)29)13-1-2-13/h11-16H,1-10H2.
What are the key properties of 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one?
1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one has a molecular weight of 409.46 g/mol, XLogP of 2.69, 5 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-cyclopropyl-3-[4-[cyclopropyl-[6-(trifluoromethyl)pyrimidin-4-yl]amino]piperidin-1-yl]pyrrolidin-2-one is sourced from PubChem (CID 126891006), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).