About 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide
2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide (PubChem CID 127052321) has the molecular formula C29H33F3N6O2
and a molecular weight of 554.62 g/mol. Its IUPAC name is 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide.
Molecular Properties
| Compound Name | 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide |
| PubChem CID | 127052321 |
| Molecular Formula | C29H33F3N6O2 |
| Molecular Weight | 554.62 g/mol |
| Exact Mass | 554.26 |
| IUPAC Name | 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide |
| SMILES | CC(C)C(=O)Nc1ccc(-c2ccc(NCC(=O)Nc3ccc(CN4CCNCC4)c(C(F)(F)F)c3)cc2)cn1 |
| InChI | InChI=1S/C29H33F3N6O2/c1-19(2)28(40)37-26-10-6-21(16-35-26)20-3-7-23(8-4-20)34-17-27(39)36-24-9-5-22(25(15-24)29(30,31)32)18-38-13-11-33-12-14-38/h3-10,15-16,19,33-34H,11-14,17-18H2,1-2H3,(H,36,39)(H,35,37,40) |
| InChIKey | LLDMEDJNOJVTEE-UHFFFAOYSA-N |
| XLogP | 4.82 |
| TPSA | 98.39 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Heavy Atoms | 40 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 554.62 |
| LogP ≤ 5 | 4.82 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide?
The IUPAC name of 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide (CID 127052321) is 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide.
What is the SMILES notation for 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide?
The canonical SMILES for 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide is CC(C)C(=O)Nc1ccc(-c2ccc(NCC(=O)Nc3ccc(CN4CCNCC4)c(C(F)(F)F)c3)cc2)cn1.
What is the InChIKey of 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide?
The InChIKey is LLDMEDJNOJVTEE-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H33F3N6O2/c1-19(2)28(40)37-26-10-6-21(16-35-26)20-3-7-23(8-4-20)34-17-27(39)36-24-9-5-22(25(15-24)29(30,31)32)18-38-13-11-33-12-14-38/h3-10,15-16,19,33-34H,11-14,17-18H2,1-2H3,(H,36,39)(H,35,37,40).
What are the key properties of 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide?
2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide has a molecular weight of 554.62 g/mol, XLogP of 4.82, 9 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-methyl-N-[5-[4-[[2-oxo-2-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)anilino]ethyl]amino]phenyl]-2-pyridinyl]propanamide is sourced from PubChem (CID 127052321), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).