(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide

C18H18N4O2S — CID 128967401

IUPAC(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
SMILESCc1csc(NC(=O)[C@H]2CCO[C@@H]2c2cnn(-c3ccccc3)c2)n1
InChIInChI=1S/C18H18N4O2S/c1-12-11-25-18(20-12)21-17(23)15-7-8-24-16(15)13-9-19-22(10-13)14-5-3-2-4-6-14/h2-6,9-11,15-16H,7-8H2,1H3,(H,20,21,23)/t15-,16+/m0/s1
InChIKeyUQIDXVOQIXAROL-JKSUJKDBSA-N
MW354.44 g/mol
LogP3.35
Rot. Bonds4

About (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide

(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide (PubChem CID 128967401) has the molecular formula C18H18N4O2S and a molecular weight of 354.44 g/mol. Its IUPAC name is (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide.

Molecular Properties

Compound Name(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
PubChem CID128967401
Molecular FormulaC18H18N4O2S
Molecular Weight354.44 g/mol
Exact Mass354.12
IUPAC Name(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
SMILESCc1csc(NC(=O)[C@H]2CCO[C@@H]2c2cnn(-c3ccccc3)c2)n1
InChIInChI=1S/C18H18N4O2S/c1-12-11-25-18(20-12)21-17(23)15-7-8-24-16(15)13-9-19-22(10-13)14-5-3-2-4-6-14/h2-6,9-11,15-16H,7-8H2,1H3,(H,20,21,23)/t15-,16+/m0/s1
InChIKeyUQIDXVOQIXAROL-JKSUJKDBSA-N
XLogP3.35
TPSA69.04 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500354.44
LogP ≤ 53.35
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

Analyze (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(2S,3S)-N-(1-methyl-6-oxo-3-pyridinyl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
CID 128966167
(2S,3S)-N-(4-methyl-3-oxo-1,4-benzoxazin-6-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
CID 128966138
(2S,3S)-N-[(2R)-2-methyl-3-(2-methylimidazol-1-yl)propyl]-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
CID 129323627
(2S,3S)-N-methyl-N-[(5-methylfuran-2-yl)methyl]-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide
CID 128966174
(3R,4S)-4-(1-methylpyrazol-4-yl)-N-(4-methyl-1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CID 120917398
(2S,3S)-2-(1-ethylpyrazol-4-yl)-N-(3-methyl-1,2-thiazol-5-yl)oxolane-3-carboxamide
CID 128996390
(2S,3S)-N-(6-methoxy-2-methyl-3-pyridinyl)-2-(1-methylpyrazol-4-yl)oxolane-3-carboxamide
CID 128973421
(2S,3S)-N-[5-(4-methylphenyl)-1H-1,2,4-triazol-3-yl]-2-(1-propan-2-ylpyrazol-4-yl)oxolane-3-carboxamide
CID 128969422
1-(1,3-diphenylpyrazole-4-carbonyl)-N-(4-methyl-1,3-thiazol-2-yl)piperidine-4-carboxamide
CID 55950995
(2S)-N-(4-methyl-1,3-thiazol-2-yl)oxolane-2-carboxamide
CID 1086809
(2S,3S)-2-(1-ethylpyrazol-4-yl)-N-(thiophen-2-ylmethyl)oxolane-3-carboxamide
CID 129005643
(1R,2R,4R)-N-(4-methyl-1,3-thiazol-2-yl)bicyclo[2.2.1]heptane-2-carboxamide
CID 98277438

Frequently Asked Questions

What is the IUPAC name of (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide?
The IUPAC name of (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide (CID 128967401) is (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide.
What is the SMILES notation for (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide?
The canonical SMILES for (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide is Cc1csc(NC(=O)[C@H]2CCO[C@@H]2c2cnn(-c3ccccc3)c2)n1.
What is the InChIKey of (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide?
The InChIKey is UQIDXVOQIXAROL-JKSUJKDBSA-N. The full InChI is InChI=1S/C18H18N4O2S/c1-12-11-25-18(20-12)21-17(23)15-7-8-24-16(15)13-9-19-22(10-13)14-5-3-2-4-6-14/h2-6,9-11,15-16H,7-8H2,1H3,(H,20,21,23)/t15-,16+/m0/s1.
What are the key properties of (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide?
(2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide has a molecular weight of 354.44 g/mol, XLogP of 3.35, 4 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for (2S,3S)-N-(4-methyl-1,3-thiazol-2-yl)-2-(1-phenylpyrazol-4-yl)oxolane-3-carboxamide is sourced from PubChem (CID 128967401), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).