About 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide
2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide (PubChem CID 129077236) has the molecular formula C27H27ClFN5O4
and a molecular weight of 540.00 g/mol. Its IUPAC name is 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide.
Molecular Properties
| Compound Name | 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide |
| PubChem CID | 129077236 |
| Molecular Formula | C27H27ClFN5O4 |
| Molecular Weight | 540.00 g/mol |
| Exact Mass | 539.17 |
| IUPAC Name | 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide |
| SMILES | COc1ccc(F)cc1CNC(=O)CN1Cc2ccc(-c3nc(NC4CCOCC4)ncc3Cl)cc2C1=O |
| InChI | InChI=1S/C27H27ClFN5O4/c1-37-23-5-4-19(29)10-18(23)12-30-24(35)15-34-14-17-3-2-16(11-21(17)26(34)36)25-22(28)13-31-27(33-25)32-20-6-8-38-9-7-20/h2-5,10-11,13,20H,6-9,12,14-15H2,1H3,(H,30,35)(H,31,32,33) |
| InChIKey | BFZQRNGZJPHEJM-UHFFFAOYSA-N |
| XLogP | 3.81 |
| TPSA | 105.68 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 38 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 540.00 |
| LogP ≤ 5 | 3.81 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide?
The IUPAC name of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide (CID 129077236) is 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide.
What is the SMILES notation for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide?
The canonical SMILES for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide is COc1ccc(F)cc1CNC(=O)CN1Cc2ccc(-c3nc(NC4CCOCC4)ncc3Cl)cc2C1=O.
What is the InChIKey of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide?
The InChIKey is BFZQRNGZJPHEJM-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27ClFN5O4/c1-37-23-5-4-19(29)10-18(23)12-30-24(35)15-34-14-17-3-2-16(11-21(17)26(34)36)25-22(28)13-31-27(33-25)32-20-6-8-38-9-7-20/h2-5,10-11,13,20H,6-9,12,14-15H2,1H3,(H,30,35)(H,31,32,33).
What are the key properties of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide?
2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide has a molecular weight of 540.00 g/mol, XLogP of 3.81, 8 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(5-fluoro-2-methoxyphenyl)methyl]acetamide is sourced from PubChem (CID 129077236), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).