About 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide
2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide (PubChem CID 129077987) has the molecular formula C28H29ClFN5O4
and a molecular weight of 554.02 g/mol. Its IUPAC name is 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide.
Molecular Properties
| Compound Name | 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide |
| PubChem CID | 129077987 |
| Molecular Formula | C28H29ClFN5O4 |
| Molecular Weight | 554.02 g/mol |
| Exact Mass | 553.19 |
| IUPAC Name | 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide |
| SMILES | COc1cc(C(C)NC(=O)CN2Cc3ccc(-c4nc(NC5CCOCC5)ncc4Cl)cc3C2=O)ccc1F |
| InChI | InChI=1S/C28H29ClFN5O4/c1-16(17-5-6-23(30)24(12-17)38-2)32-25(36)15-35-14-19-4-3-18(11-21(19)27(35)37)26-22(29)13-31-28(34-26)33-20-7-9-39-10-8-20/h3-6,11-13,16,20H,7-10,14-15H2,1-2H3,(H,32,36)(H,31,33,34) |
| InChIKey | BPCYNUMVYHIEHC-UHFFFAOYSA-N |
| XLogP | 4.37 |
| TPSA | 105.68 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 39 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 554.02 |
| LogP ≤ 5 | 4.37 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide?
The IUPAC name of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide (CID 129077987) is 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide.
What is the SMILES notation for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide?
The canonical SMILES for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide is COc1cc(C(C)NC(=O)CN2Cc3ccc(-c4nc(NC5CCOCC5)ncc4Cl)cc3C2=O)ccc1F.
What is the InChIKey of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide?
The InChIKey is BPCYNUMVYHIEHC-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29ClFN5O4/c1-16(17-5-6-23(30)24(12-17)38-2)32-25(36)15-35-14-19-4-3-18(11-21(19)27(35)37)26-22(29)13-31-28(34-26)33-20-7-9-39-10-8-20/h3-6,11-13,16,20H,7-10,14-15H2,1-2H3,(H,32,36)(H,31,33,34).
What are the key properties of 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide?
2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide has a molecular weight of 554.02 g/mol, XLogP of 4.37, 8 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[1-(4-fluoro-3-methoxyphenyl)ethyl]acetamide is sourced from PubChem (CID 129077987), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).