About 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea
1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea (PubChem CID 1297290) has the molecular formula C16H16ClFN2O2S
and a molecular weight of 354.83 g/mol. Its IUPAC name is 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea.
Molecular Properties
| Compound Name | 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea |
| PubChem CID | 1297290 |
| Molecular Formula | C16H16ClFN2O2S |
| Molecular Weight | 354.83 g/mol |
| Exact Mass | 354.06 |
| IUPAC Name | 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea |
| SMILES | COc1ccc(CNC(=S)Nc2ccc(F)c(Cl)c2)cc1OC |
| InChI | InChI=1S/C16H16ClFN2O2S/c1-21-14-6-3-10(7-15(14)22-2)9-19-16(23)20-11-4-5-13(18)12(17)8-11/h3-8H,9H2,1-2H3,(H2,19,20,23) |
| InChIKey | UJSLYVRZACPZRK-UHFFFAOYSA-N |
| XLogP | 3.98 |
| TPSA | 42.52 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 23 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 354.83 |
| LogP ≤ 5 | 3.98 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 3 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea?
The IUPAC name of 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea (CID 1297290) is 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea.
What is the SMILES notation for 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea?
The canonical SMILES for 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea is COc1ccc(CNC(=S)Nc2ccc(F)c(Cl)c2)cc1OC.
What is the InChIKey of 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea?
The InChIKey is UJSLYVRZACPZRK-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H16ClFN2O2S/c1-21-14-6-3-10(7-15(14)22-2)9-19-16(23)20-11-4-5-13(18)12(17)8-11/h3-8H,9H2,1-2H3,(H2,19,20,23).
What are the key properties of 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea?
1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea has a molecular weight of 354.83 g/mol, XLogP of 3.98, 5 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(3-chloro-4-fluorophenyl)-3-[(3,4-dimethoxyphenyl)methyl]thiourea is sourced from PubChem (CID 1297290), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).