About 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea
1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea (PubChem CID 1298134) has the molecular formula C16H15ClF2N2OS
and a molecular weight of 356.83 g/mol. Its IUPAC name is 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea.
Molecular Properties
| Compound Name | 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea |
| PubChem CID | 1298134 |
| Molecular Formula | C16H15ClF2N2OS |
| Molecular Weight | 356.83 g/mol |
| Exact Mass | 356.06 |
| IUPAC Name | 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea |
| SMILES | Cc1cc(OC(F)F)ccc1NC(=S)Nc1cc(Cl)ccc1C |
| InChI | InChI=1S/C16H15ClF2N2OS/c1-9-3-4-11(17)8-14(9)21-16(23)20-13-6-5-12(7-10(13)2)22-15(18)19/h3-8,15H,1-2H3,(H2,20,21,23) |
| InChIKey | CZSQFHSPHWYEQQ-UHFFFAOYSA-N |
| XLogP | 5.37 |
| TPSA | 33.29 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 23 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 356.83 |
| LogP ≤ 5 | 5.37 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 2 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea?
The IUPAC name of 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea (CID 1298134) is 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea.
What is the SMILES notation for 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea?
The canonical SMILES for 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea is Cc1cc(OC(F)F)ccc1NC(=S)Nc1cc(Cl)ccc1C.
What is the InChIKey of 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea?
The InChIKey is CZSQFHSPHWYEQQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H15ClF2N2OS/c1-9-3-4-11(17)8-14(9)21-16(23)20-13-6-5-12(7-10(13)2)22-15(18)19/h3-8,15H,1-2H3,(H2,20,21,23).
What are the key properties of 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea?
1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea has a molecular weight of 356.83 g/mol, XLogP of 5.37, 4 rotatable bonds, 2 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(5-chloro-2-methylphenyl)-3-[4-(difluoromethoxy)-2-methylphenyl]thiourea is sourced from PubChem (CID 1298134), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).