About 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid
2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid (PubChem CID 134431246) has the molecular formula C21H22N4O3
and a molecular weight of 378.43 g/mol. Its IUPAC name is 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid.
Molecular Properties
| Compound Name | 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid |
| PubChem CID | 134431246 |
| Molecular Formula | C21H22N4O3 |
| Molecular Weight | 378.43 g/mol |
| Exact Mass | 378.17 |
| IUPAC Name | 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid |
| SMILES | Cc1cc(C2CC2C(=O)O)ccc1-c1cc2nc(C(=O)N(C)C)cc(C)n2n1 |
| InChI | InChI=1S/C21H22N4O3/c1-11-7-13(15-9-16(15)21(27)28)5-6-14(11)17-10-19-22-18(20(26)24(3)4)8-12(2)25(19)23-17/h5-8,10,15-16H,9H2,1-4H3,(H,27,28) |
| InChIKey | OVAAYKHESFFPQZ-UHFFFAOYSA-N |
| XLogP | 2.90 |
| TPSA | 87.80 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 378.43 |
| LogP ≤ 5 | 2.90 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid?
The IUPAC name of 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid (CID 134431246) is 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid.
What is the SMILES notation for 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid?
The canonical SMILES for 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid is Cc1cc(C2CC2C(=O)O)ccc1-c1cc2nc(C(=O)N(C)C)cc(C)n2n1.
What is the InChIKey of 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid?
The InChIKey is OVAAYKHESFFPQZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H22N4O3/c1-11-7-13(15-9-16(15)21(27)28)5-6-14(11)17-10-19-22-18(20(26)24(3)4)8-12(2)25(19)23-17/h5-8,10,15-16H,9H2,1-4H3,(H,27,28).
What are the key properties of 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid?
2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid has a molecular weight of 378.43 g/mol, XLogP of 2.90, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[5-(dimethylcarbamoyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]-3-methylphenyl]cyclopropane-1-carboxylic acid is sourced from PubChem (CID 134431246), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).