About [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone
[(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone (PubChem CID 134517350) has the molecular formula C19H22F2N6O
and a molecular weight of 388.42 g/mol. Its IUPAC name is [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone.
Molecular Properties
| Compound Name | [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone |
| PubChem CID | 134517350 |
| Molecular Formula | C19H22F2N6O |
| Molecular Weight | 388.42 g/mol |
| Exact Mass | 388.18 |
| IUPAC Name | [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone |
| SMILES | CC1([C@@H]2CC=NN2C(=O)C2CCN(c3ncc(F)cn3)CC2)C=NC=C(F)C1 |
| InChI | InChI=1S/C19H22F2N6O/c1-19(8-14(20)9-22-12-19)16-2-5-25-27(16)17(28)13-3-6-26(7-4-13)18-23-10-15(21)11-24-18/h5,9-13,16H,2-4,6-8H2,1H3/t16-,19?/m0/s1 |
| InChIKey | DDKVJZGLCPXHTJ-UCFFOFKASA-N |
| XLogP | 2.71 |
| TPSA | 74.05 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 388.42 |
| LogP ≤ 5 | 2.71 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone?
The IUPAC name of [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone (CID 134517350) is [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone.
What is the SMILES notation for [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone?
The canonical SMILES for [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone is CC1([C@@H]2CC=NN2C(=O)C2CCN(c3ncc(F)cn3)CC2)C=NC=C(F)C1.
What is the InChIKey of [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone?
The InChIKey is DDKVJZGLCPXHTJ-UCFFOFKASA-N. The full InChI is InChI=1S/C19H22F2N6O/c1-19(8-14(20)9-22-12-19)16-2-5-25-27(16)17(28)13-3-6-26(7-4-13)18-23-10-15(21)11-24-18/h5,9-13,16H,2-4,6-8H2,1H3/t16-,19?/m0/s1.
What are the key properties of [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone?
[(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone has a molecular weight of 388.42 g/mol, XLogP of 2.71, 3 rotatable bonds, 0 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for [(3S)-3-(5-fluoro-3-methyl-4H-pyridin-3-yl)-3,4-dihydropyrazol-2-yl]-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]methanone is sourced from PubChem (CID 134517350), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).