About N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide
N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide (PubChem CID 134609355) has the molecular formula C26H27F2N3O4
and a molecular weight of 483.52 g/mol. Its IUPAC name is N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide.
Molecular Properties
| Compound Name | N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide |
| PubChem CID | 134609355 |
| Molecular Formula | C26H27F2N3O4 |
| Molecular Weight | 483.52 g/mol |
| Exact Mass | 483.20 |
| IUPAC Name | N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide |
| SMILES | Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OCCO)c(C2(F)COC2)c1 |
| InChI | InChI=1S/C26H27F2N3O4/c1-16-4-5-19(31-23(33)17-6-7-29-22(11-17)25(2,3)27)12-20(16)18-10-21(26(28)14-34-15-26)24(30-13-18)35-9-8-32/h4-7,10-13,32H,8-9,14-15H2,1-3H3,(H,31,33) |
| InChIKey | TXKYMVOKGCIMRU-UHFFFAOYSA-N |
| XLogP | 4.48 |
| TPSA | 93.57 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 35 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 483.52 |
| LogP ≤ 5 | 4.48 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide?
The IUPAC name of N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide (CID 134609355) is N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide.
What is the SMILES notation for N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide?
The canonical SMILES for N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide is Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OCCO)c(C2(F)COC2)c1.
What is the InChIKey of N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide?
The InChIKey is TXKYMVOKGCIMRU-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H27F2N3O4/c1-16-4-5-19(31-23(33)17-6-7-29-22(11-17)25(2,3)27)12-20(16)18-10-21(26(28)14-34-15-26)24(30-13-18)35-9-8-32/h4-7,10-13,32H,8-9,14-15H2,1-3H3,(H,31,33).
What are the key properties of N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide?
N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide has a molecular weight of 483.52 g/mol, XLogP of 4.48, 8 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[5-(3-fluorooxetan-3-yl)-6-(2-hydroxyethoxy)-3-pyridinyl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide is sourced from PubChem (CID 134609355), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).