About N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 134609375) has the molecular formula C25H24F3N3O5
and a molecular weight of 503.48 g/mol. Its IUPAC name is N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.
Molecular Properties
| Compound Name | N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide |
| PubChem CID | 134609375 |
| Molecular Formula | C25H24F3N3O5 |
| Molecular Weight | 503.48 g/mol |
| Exact Mass | 503.17 |
| IUPAC Name | N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide |
| SMILES | COC1(c2cc(-c3cc(NC(=O)c4ccnc(C(F)(F)F)c4)ccc3C)cnc2OCCO)COC1 |
| InChI | InChI=1S/C25H24F3N3O5/c1-15-3-4-18(31-22(33)16-5-6-29-21(10-16)25(26,27)28)11-19(15)17-9-20(24(34-2)13-35-14-24)23(30-12-17)36-8-7-32/h3-6,9-12,32H,7-8,13-14H2,1-2H3,(H,31,33) |
| InChIKey | XQWHABXRIJEOOS-UHFFFAOYSA-N |
| XLogP | 3.97 |
| TPSA | 102.80 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 36 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 503.48 |
| LogP ≤ 5 | 3.97 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The IUPAC name of N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 134609375) is N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.
What is the SMILES notation for N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The canonical SMILES for N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is COC1(c2cc(-c3cc(NC(=O)c4ccnc(C(F)(F)F)c4)ccc3C)cnc2OCCO)COC1.
What is the InChIKey of N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The InChIKey is XQWHABXRIJEOOS-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H24F3N3O5/c1-15-3-4-18(31-22(33)16-5-6-29-21(10-16)25(26,27)28)11-19(15)17-9-20(24(34-2)13-35-14-24)23(30-12-17)36-8-7-32/h3-6,9-12,32H,7-8,13-14H2,1-2H3,(H,31,33).
What are the key properties of N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 503.48 g/mol, XLogP of 3.97, 8 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[6-(2-hydroxyethoxy)-5-(3-methoxyoxetan-3-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 134609375), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).