3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid

C33H35Cl2FN2O5 — CID 135281444

IUPAC3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid
SMILESCC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(CCC(=O)O)CC1
InChIInChI=1S/C33H35Cl2FN2O5/c1-3-32(42,22-12-15-37(16-13-22)17-14-29(39)40)24-18-27-30(28(36)19-24)33(43-2,23-6-10-26(35)11-7-23)38(31(27)41)20-21-4-8-25(34)9-5-21/h4-11,18-19,22,42H,3,12-17,20H2,1-2H3,(H,39,40)/t32-,33+/m0/s1
InChIKeyZKUGFHUACFYRES-JHOUSYSJSA-N
MW629.56 g/mol
LogP6.42
Rot. Bonds10

About 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid

3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid (PubChem CID 135281444) has the molecular formula C33H35Cl2FN2O5 and a molecular weight of 629.56 g/mol. Its IUPAC name is 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid.

Molecular Properties

Compound Name3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid
PubChem CID135281444
Molecular FormulaC33H35Cl2FN2O5
Molecular Weight629.56 g/mol
Exact Mass628.19
IUPAC Name3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid
SMILESCC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(CCC(=O)O)CC1
InChIInChI=1S/C33H35Cl2FN2O5/c1-3-32(42,22-12-15-37(16-13-22)17-14-29(39)40)24-18-27-30(28(36)19-24)33(43-2,23-6-10-26(35)11-7-23)38(31(27)41)20-21-4-8-25(34)9-5-21/h4-11,18-19,22,42H,3,12-17,20H2,1-2H3,(H,39,40)/t32-,33+/m0/s1
InChIKeyZKUGFHUACFYRES-JHOUSYSJSA-N
XLogP6.42
TPSA90.31 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds10
Heavy Atoms43
Complexity—

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500629.56
LogP ≤ 56.42
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Analyze 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid with MolForge

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Related Compounds

(2S,3S)-3-(4-chlorophenyl)-3-((R)-1-(4-chlorophenyl)-7-fluoro-5-((S)-1-hydroxy-1-(tetrahydro-2H-pyran-4-yl)propyl)-1-methoxy-3-oxoisoindolin-2-yl)-2-methylpropanoic acid
CID 135281467
US10544132, Example 16
CID 135281465
US10544132, Example 1
CID 135281635
US10544132, Example 2
CID 135281669
(3R)-3-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-3-[dideuterio-[1-[dideuterio(hydroxy)methyl]cyclopropyl]methoxy]-6-(2-hydroxypropan-2-yl)isoindol-1-one
CID 145765584
4-[[(1R)-1-(4-chlorophenyl)-1-[dideuterio-[1-[dideuterio(hydroxy)methyl]cyclopropyl]methoxy]-7-fluoro-5-(2-hydroxypropan-2-yl)-3-oxoisoindol-2-yl]methyl]benzonitrile
CID 145765596
US11236047, Example 98
CID 135281416
US11236047, Example 88
CID 135281674
US10544132, Example 136
CID 135281761
US10544132, Example 88
CID 154732995
US10544132, Example 98
CID 154733005
US10544132, Example 137
CID 154733018

Frequently Asked Questions

What is the IUPAC name of 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid?
The IUPAC name of 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid (CID 135281444) is 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid.
What is the SMILES notation for 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid?
The canonical SMILES for 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid is CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(CCC(=O)O)CC1.
What is the InChIKey of 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid?
The InChIKey is ZKUGFHUACFYRES-JHOUSYSJSA-N. The full InChI is InChI=1S/C33H35Cl2FN2O5/c1-3-32(42,22-12-15-37(16-13-22)17-14-29(39)40)24-18-27-30(28(36)19-24)33(43-2,23-6-10-26(35)11-7-23)38(31(27)41)20-21-4-8-25(34)9-5-21/h4-11,18-19,22,42H,3,12-17,20H2,1-2H3,(H,39,40)/t32-,33+/m0/s1.
What are the key properties of 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid?
3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid has a molecular weight of 629.56 g/mol, XLogP of 6.42, 10 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[4-[(1S)-1-[(1R)-1-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]-7-fluoro-1-methoxy-3-oxoisoindol-5-yl]-1-hydroxypropyl]piperidin-1-yl]propanoic acid is sourced from PubChem (CID 135281444), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).