About [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone
[4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone (PubChem CID 135281787) has the molecular formula C26H25ClN4O4
and a molecular weight of 492.96 g/mol. Its IUPAC name is [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone.
Molecular Properties
| Compound Name | [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone |
| PubChem CID | 135281787 |
| Molecular Formula | C26H25ClN4O4 |
| Molecular Weight | 492.96 g/mol |
| Exact Mass | 492.16 |
| IUPAC Name | [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone |
| SMILES | COc1cc(OC)c(-c2cn3ccc(N4CCN(C(=O)c5ccccc5O)CC4)cc3n2)cc1Cl |
| InChI | InChI=1S/C26H25ClN4O4/c1-34-23-15-24(35-2)20(27)14-19(23)21-16-31-8-7-17(13-25(31)28-21)29-9-11-30(12-10-29)26(33)18-5-3-4-6-22(18)32/h3-8,13-16,32H,9-12H2,1-2H3 |
| InChIKey | RQCSRGLEFOAQPR-UHFFFAOYSA-N |
| XLogP | 4.34 |
| TPSA | 79.54 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 35 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 492.96 |
| LogP ≤ 5 | 4.34 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone?
The IUPAC name of [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone (CID 135281787) is [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone.
What is the SMILES notation for [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone?
The canonical SMILES for [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone is COc1cc(OC)c(-c2cn3ccc(N4CCN(C(=O)c5ccccc5O)CC4)cc3n2)cc1Cl.
What is the InChIKey of [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone?
The InChIKey is RQCSRGLEFOAQPR-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25ClN4O4/c1-34-23-15-24(35-2)20(27)14-19(23)21-16-31-8-7-17(13-25(31)28-21)29-9-11-30(12-10-29)26(33)18-5-3-4-6-22(18)32/h3-8,13-16,32H,9-12H2,1-2H3.
What are the key properties of [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone?
[4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone has a molecular weight of 492.96 g/mol, XLogP of 4.34, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for [4-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]piperazin-1-yl]-(2-hydroxyphenyl)methanone is sourced from PubChem (CID 135281787), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).