4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine

C64H70ClN19O4 — CID 135314322

IUPAC4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine
SMILESCC(C)(C)n1cc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cn1.CCOc1ncc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cc1Cl.c1cc(-c2nccc3c(N4CCCCC4)cc(N4CCOCC4)nc23)[nH]n1
InChIInChI=1S/C22H21ClN6O2.C22H25N7O.C20H24N6O/c1-2-31-22-17(23)11-14(13-25-22)16-12-19(29-7-9-30-10-8-29)27-20-15(16)3-5-24-21(20)18-4-6-26-28-18;1-22(2,3)29-14-15(13-25-29)17-12-19(28-8-10-30-11-9-28)26-20-16(17)4-6-23-21(20)18-5-7-24-27-18;1-2-8-25(9-3-1)17-14-18(26-10-12-27-13-11-26)23-19-15(17)4-6-21-20(19)16-5-7-22-24-16/h3-6,11-13H,2,7-10H2,1H3,(H,26,28);4-7,12-14H,8-11H2,1-3H3,(H,24,27);4-7,14H,1-3,8-13H2,(H,22,24)
InChIKeySUCCCCDTRLQPEO-UHFFFAOYSA-N
MW1204.85 g/mol
LogP10.29
Rot. Bonds11

About 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine

4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine (PubChem CID 135314322) has the molecular formula C64H70ClN19O4 and a molecular weight of 1204.85 g/mol. Its IUPAC name is 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine.

Molecular Properties

Compound Name4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine
PubChem CID135314322
Molecular FormulaC64H70ClN19O4
Molecular Weight1204.85 g/mol
Exact Mass1203.55
IUPAC Name4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine
SMILESCC(C)(C)n1cc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cn1.CCOc1ncc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cc1Cl.c1cc(-c2nccc3c(N4CCCCC4)cc(N4CCOCC4)nc23)[nH]n1
InChIInChI=1S/C22H21ClN6O2.C22H25N7O.C20H24N6O/c1-2-31-22-17(23)11-14(13-25-22)16-12-19(29-7-9-30-10-8-29)27-20-15(16)3-5-24-21(20)18-4-6-26-28-18;1-22(2,3)29-14-15(13-25-29)17-12-19(28-8-10-30-11-9-28)26-20-16(17)4-6-23-21(20)18-5-7-24-27-18;1-2-8-25(9-3-1)17-14-18(26-10-12-27-13-11-26)23-19-15(17)4-6-21-20(19)16-5-7-22-24-16/h3-6,11-13H,2,7-10H2,1H3,(H,26,28);4-7,12-14H,8-11H2,1-3H3,(H,24,27);4-7,14H,1-3,8-13H2,(H,22,24)
InChIKeySUCCCCDTRLQPEO-UHFFFAOYSA-N
XLogP10.29
TPSA243.97 Ų
H-Bond Donors3
H-Bond Acceptors20
Rotatable Bonds11
Heavy Atoms88
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001204.85
LogP ≤ 510.29
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1020

Analyze 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-(2-ethoxypyridin-3-yl)-2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
CID 118869414
4-(3-chloro-2-methoxypyridin-4-yl)-2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
CID 118869430
(3R)-4-[4-(2-methoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]-3-methylmorpholine
CID 118869604
(3R)-3-methyl-4-[4-(2-propan-2-yloxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine
CID 118869643
4-(6-ethoxypyridin-3-yl)-2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
CID 118869666
4-(5-chloro-6-ethoxypyridin-3-yl)-2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
CID 122585593
2-(morpholin-4-yl)-4-[2-(propan-2-yloxy)pyridin-3-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine
CID 122585608
US10729680, Example 50
CID 130228623
US10729680, Example 27
CID 130228977
4-(3-chloro-2-methoxypyridin-4-yl)-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-napthyridine
CID 135121231
(3R)-4-[4-(6-methoxy-5-methyl-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]-3-methylmorpholine
CID 118869135
4-(2-Methoxy-4-pyridinyl)-2-(4-morpholinyl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine
CID 118869271

Frequently Asked Questions

What is the IUPAC name of 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine?
The IUPAC name of 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine (CID 135314322) is 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine.
What is the SMILES notation for 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine?
The canonical SMILES for 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine is CC(C)(C)n1cc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cn1.CCOc1ncc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cc1Cl.c1cc(-c2nccc3c(N4CCCCC4)cc(N4CCOCC4)nc23)[nH]n1.
What is the InChIKey of 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine?
The InChIKey is SUCCCCDTRLQPEO-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H21ClN6O2.C22H25N7O.C20H24N6O/c1-2-31-22-17(23)11-14(13-25-22)16-12-19(29-7-9-30-10-8-29)27-20-15(16)3-5-24-21(20)18-4-6-26-28-18;1-22(2,3)29-14-15(13-25-29)17-12-19(28-8-10-30-11-9-28)26-20-16(17)4-6-23-21(20)18-5-7-24-27-18;1-2-8-25(9-3-1)17-14-18(26-10-12-27-13-11-26)23-19-15(17)4-6-21-20(19)16-5-7-22-24-16/h3-6,11-13H,2,7-10H2,1H3,(H,26,28);4-7,12-14H,8-11H2,1-3H3,(H,24,27);4-7,14H,1-3,8-13H2,(H,22,24).
What are the key properties of 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine?
4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine has a molecular weight of 1204.85 g/mol, XLogP of 10.29, 11 rotatable bonds, 3 hydrogen bond donors, and 20 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[4-(1-tert-butylpyrazol-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-(5-chloro-6-ethoxy-3-pyridinyl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;4-[4-piperidin-1-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine is sourced from PubChem (CID 135314322), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).