N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide

C18H15N3O2 — CID 135455081

IUPACN-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide
SMILESO=C(Cc1ccccc1)N/N=C/c1ccc2cccc(O)c2n1
InChIInChI=1S/C18H15N3O2/c22-16-8-4-7-14-9-10-15(20-18(14)16)12-19-21-17(23)11-13-5-2-1-3-6-13/h1-10,12,22H,11H2,(H,21,23)/b19-12+
InChIKeyGLDICASPVYQGJH-XDHOZWIPSA-N
MW305.34 g/mol
LogP2.63
Rot. Bonds4

About N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide

N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide (PubChem CID 135455081) has the molecular formula C18H15N3O2 and a molecular weight of 305.34 g/mol. Its IUPAC name is N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide.

Molecular Properties

Compound NameN-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide
PubChem CID135455081
Molecular FormulaC18H15N3O2
Molecular Weight305.34 g/mol
Exact Mass305.12
IUPAC NameN-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide
SMILESO=C(Cc1ccccc1)N/N=C/c1ccc2cccc(O)c2n1
InChIInChI=1S/C18H15N3O2/c22-16-8-4-7-14-9-10-15(20-18(14)16)12-19-21-17(23)11-13-5-2-1-3-6-13/h1-10,12,22H,11H2,(H,21,23)/b19-12+
InChIKeyGLDICASPVYQGJH-XDHOZWIPSA-N
XLogP2.63
TPSA74.58 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500305.34
LogP ≤ 52.63
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'imine_1', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

8-Quinolinol, benzoate (1:1)
CID 62626
N'-((8-Hydroxy-2-quinolinyl)methylene)-3-phenylpropanohydrazide
CID 135479710
2-Quinolinecarboxaldehyde, 8-hydroxy-, oxime
CID 135439621
2-[(E)-2-(3-hydroxyphenyl)ethenyl]quinolin-8-ol
CID 5837141
8-Hydroxyquinoline-2-carboxamide
CID 2831986
2-(4-Hydroxystyryl)quinolin-8-ol
CID 135500760
N-[(8-hydroxyquinolin-7-yl)(phenyl)methyl]-2-phenylacetamide
CID 2877003
N'-[(E)-(8-hydroxyquinolin-5-yl)methylidene]-3-phenylpropanehydrazide
CID 135404086
N'-[(1E)-(4-hydroxyphenyl)methylene]-2-phenylquinoline-4-carbohydrazide
CID 135501377
4-[2-(8-Hydroxy-2-quinolinyl)vinyl]benzoic acid
CID 5730126
N-[(E)-(3-hydroxyphenyl)methylideneamino]-2-phenylquinoline-4-carboxamide
CID 6882669
3-bromo-N'-[(E)-(8-hydroxyquinolin-5-yl)methylidene]benzohydrazide
CID 135404087

Frequently Asked Questions

What is the IUPAC name of N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide?
The IUPAC name of N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide (CID 135455081) is N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide.
What is the SMILES notation for N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide?
The canonical SMILES for N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide is O=C(Cc1ccccc1)N/N=C/c1ccc2cccc(O)c2n1.
What is the InChIKey of N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide?
The InChIKey is GLDICASPVYQGJH-XDHOZWIPSA-N. The full InChI is InChI=1S/C18H15N3O2/c22-16-8-4-7-14-9-10-15(20-18(14)16)12-19-21-17(23)11-13-5-2-1-3-6-13/h1-10,12,22H,11H2,(H,21,23)/b19-12+.
What are the key properties of N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide?
N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide has a molecular weight of 305.34 g/mol, XLogP of 2.63, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(E)-(8-hydroxyquinolin-2-yl)methylideneamino]-2-phenylacetamide is sourced from PubChem (CID 135455081), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).