About 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one
2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one (PubChem CID 135948820) has the molecular formula C22H17F3N4O3
and a molecular weight of 442.40 g/mol. Its IUPAC name is 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one.
Molecular Properties
| Compound Name | 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one |
| PubChem CID | 135948820 |
| Molecular Formula | C22H17F3N4O3 |
| Molecular Weight | 442.40 g/mol |
| Exact Mass | 442.13 |
| IUPAC Name | 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one |
| SMILES | COc1ccccc1CCn1c(-c2ncccc2O)nc2ccnc(C(F)(F)F)c2c1=O |
| InChI | InChI=1S/C22H17F3N4O3/c1-32-16-7-3-2-5-13(16)9-12-29-20(18-15(30)6-4-10-26-18)28-14-8-11-27-19(22(23,24)25)17(14)21(29)31/h2-8,10-11,30H,9,12H2,1H3 |
| InChIKey | IFZAYKPXZGFSLR-UHFFFAOYSA-N |
| XLogP | 3.83 |
| TPSA | 90.13 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 442.40 |
| LogP ≤ 5 | 3.83 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one?
The IUPAC name of 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one (CID 135948820) is 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one.
What is the SMILES notation for 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one?
The canonical SMILES for 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one is COc1ccccc1CCn1c(-c2ncccc2O)nc2ccnc(C(F)(F)F)c2c1=O.
What is the InChIKey of 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one?
The InChIKey is IFZAYKPXZGFSLR-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H17F3N4O3/c1-32-16-7-3-2-5-13(16)9-12-29-20(18-15(30)6-4-10-26-18)28-14-8-11-27-19(22(23,24)25)17(14)21(29)31/h2-8,10-11,30H,9,12H2,1H3.
What are the key properties of 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one?
2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one has a molecular weight of 442.40 g/mol, XLogP of 3.83, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(3-hydroxy-2-pyridinyl)-3-[2-(2-methoxyphenyl)ethyl]-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4-one is sourced from PubChem (CID 135948820), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).