About 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea
1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea (PubChem CID 135950052) has the molecular formula C21H21F2N5OS
and a molecular weight of 429.50 g/mol. Its IUPAC name is 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea.
Molecular Properties
| Compound Name | 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea |
| PubChem CID | 135950052 |
| Molecular Formula | C21H21F2N5OS |
| Molecular Weight | 429.50 g/mol |
| Exact Mass | 429.14 |
| IUPAC Name | 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea |
| SMILES | Oc1c(/N=N/C(=S)Nc2ccc(F)cc2)c2cc(F)ccc2n1CN1CCCCC1 |
| InChI | InChI=1S/C21H21F2N5OS/c22-14-4-7-16(8-5-14)24-21(30)26-25-19-17-12-15(23)6-9-18(17)28(20(19)29)13-27-10-2-1-3-11-27/h4-9,12,29H,1-3,10-11,13H2,(H,24,30)/b26-25+ |
| InChIKey | FOVJSSKBPAWUTE-OCEACIFDSA-N |
| XLogP | 5.55 |
| TPSA | 65.15 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 429.50 |
| LogP ≤ 5 | 5.55 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'azo_A(324)', 'substructure': 'N/A'}, {'alert_name': 'diazo_group', 'substructure': 'N/A'}, {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
|---|
Analyze 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea with MolForge
Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.
Launch Full Analysis
Frequently Asked Questions
What is the IUPAC name of 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea?
The IUPAC name of 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea (CID 135950052) is 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea.
What is the SMILES notation for 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea?
The canonical SMILES for 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea is Oc1c(/N=N/C(=S)Nc2ccc(F)cc2)c2cc(F)ccc2n1CN1CCCCC1.
What is the InChIKey of 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea?
The InChIKey is FOVJSSKBPAWUTE-OCEACIFDSA-N. The full InChI is InChI=1S/C21H21F2N5OS/c22-14-4-7-16(8-5-14)24-21(30)26-25-19-17-12-15(23)6-9-18(17)28(20(19)29)13-27-10-2-1-3-11-27/h4-9,12,29H,1-3,10-11,13H2,(H,24,30)/b26-25+.
What are the key properties of 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea?
1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea has a molecular weight of 429.50 g/mol, XLogP of 5.55, 4 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[5-fluoro-2-hydroxy-1-(piperidin-1-ylmethyl)indol-3-yl]imino-3-(4-fluorophenyl)thiourea is sourced from PubChem (CID 135950052), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).