2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide

C16H16N4O2S — CID 136962144

IUPAC2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide
SMILESCCCn1cc(NC(=O)c2cnc(-c3ccccc3O)s2)cn1
InChIInChI=1S/C16H16N4O2S/c1-2-7-20-10-11(8-18-20)19-15(22)14-9-17-16(23-14)12-5-3-4-6-13(12)21/h3-6,8-10,21H,2,7H2,1H3,(H,19,22)
InChIKeyOJRWWZNWUIQJEG-UHFFFAOYSA-N
MW328.40 g/mol
LogP3.37
Rot. Bonds5

About 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide

2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide (PubChem CID 136962144) has the molecular formula C16H16N4O2S and a molecular weight of 328.40 g/mol. Its IUPAC name is 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide.

Molecular Properties

Compound Name2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide
PubChem CID136962144
Molecular FormulaC16H16N4O2S
Molecular Weight328.40 g/mol
Exact Mass328.10
IUPAC Name2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide
SMILESCCCn1cc(NC(=O)c2cnc(-c3ccccc3O)s2)cn1
InChIInChI=1S/C16H16N4O2S/c1-2-7-20-10-11(8-18-20)19-15(22)14-9-17-16(23-14)12-5-3-4-6-13(12)21/h3-6,8-10,21H,2,7H2,1H3,(H,19,22)
InChIKeyOJRWWZNWUIQJEG-UHFFFAOYSA-N
XLogP3.37
TPSA80.04 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds5
Heavy Atoms23
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500328.40
LogP ≤ 53.37
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(R)-5-amino-N-(5-(4-aminoazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(5-fluoro-2-hydroxyphenyl)thiazole-4-carboxamide
CID 135965690
5-Amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(5-fluoro-2-hydroxyphenyl)thiazole-4-carboxamide
CID 135965692
5-amino-N-[5-(4-aminoazepan-1-yl)-1-methylpyrazol-4-yl]-2-(5-fluoro-2-hydroxyphenyl)-1,3-thiazole-4-carboxamide
CID 136385965
5-amino-N-(1-methylpyrazol-4-yl)-2-[2-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxamide
CID 144595147
N-[2-(4-hydroxyphenyl)ethyl]-2-(1,3,5-trimethylpyrazol-4-yl)-1,3-thiazole-5-carboxamide
CID 117085193
2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-4-carboxamide
CID 136962141
[3-(2-Hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazol-2-yl]-[2-(1-methylpyrazol-4-yl)-1,3-thiazol-5-yl]methanone
CID 24965716
N-benzyl-2-[1-[2-(4-hydroxyphenyl)ethyl]pyrazol-3-yl]-4-methyl-1,3-thiazole-5-carboxamide
CID 59489557
N-(2-(3-hydroxybenzyl)-4-methylthiazol-5-yl)-1-methyl-1h-pyrazole-5-carboxamide
CID 71071152
N-[(1S,2R,4R)-7-azabicyclo[2.2.1]heptan-2-yl]-2-(2-hydroxyphenyl)-1,3-thiazole-5-carboxamide
CID 136433921
N-(7-azabicyclo[2.2.1]heptan-2-yl)-2-(2-hydroxyphenyl)-1,3-thiazole-5-carboxamide
CID 136638007
N-[1-[[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]amino]butan-2-yl]-1,3-thiazole-5-carboxamide
CID 137029484

Frequently Asked Questions

What is the IUPAC name of 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide?
The IUPAC name of 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide (CID 136962144) is 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide.
What is the SMILES notation for 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide?
The canonical SMILES for 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide is CCCn1cc(NC(=O)c2cnc(-c3ccccc3O)s2)cn1.
What is the InChIKey of 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide?
The InChIKey is OJRWWZNWUIQJEG-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H16N4O2S/c1-2-7-20-10-11(8-18-20)19-15(22)14-9-17-16(23-14)12-5-3-4-6-13(12)21/h3-6,8-10,21H,2,7H2,1H3,(H,19,22).
What are the key properties of 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide?
2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide has a molecular weight of 328.40 g/mol, XLogP of 3.37, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-hydroxyphenyl)-N-(1-propylpyrazol-4-yl)-1,3-thiazole-5-carboxamide is sourced from PubChem (CID 136962144), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).